Evidence map›Paper›PMID 31848385›Full record

ArticleScientific reports2019

GIRK1 triggers multiple cancer-related pathways in the benign mammary epithelial cell line MCF10A.

Gebhard Schratter, Susanne Scheruebel, Sonja Langthaler, Katja Ester, Brigitte Pelzmann, Nassim Ghaffari-Tabrizi-Wizsy, Simin Rezania, Astrid Gorischek, Dieter Platzer, Klaus Zorn-Pauly and 9 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Narrow Leafed Lupin (Nutrients · 2023
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 4 institutions in 2 countries.

Gebhard SchratterGottfried Schatz Research Center for Cell Signaling, Metabolism and Aging, Medical University of Graz, Graz, Austria.
Susanne ScheruebelGottfried Schatz Research Center for Cell Signaling, Metabolism and Aging, Medical University of Graz, Graz, Austria.
Sonja LangthalerInstitute for Health Care Engineering with European Testing Center of Medical Devices, Graz University of Technology, Graz, Austria.
Katja EsterLaboratory of Experimental Therapy, Division of Molecular Medicine, Ruđer Bošković Institute, Bijenička 54, 10000, Zagreb, Croatia.
Brigitte PelzmannGottfried Schatz Research Center for Cell Signaling, Metabolism and Aging, Medical University of Graz, Graz, Austria.
Nassim Ghaffari-Tabrizi-WizsyInstitute of Immunology and Pathophysiology, SFL Chicken CAM Laboratory, Medical University of Graz, Graz, Austria.
Simin RezaniaGottfried Schatz Research Center for Cell Signaling, Metabolism and Aging, Medical University of Graz, Graz, Austria.
Astrid GorischekGottfried Schatz Research Center for Cell Signaling, Metabolism and Aging, Medical University of Graz, Graz, Austria.
Dieter PlatzerGottfried Schatz Research Center for Cell Signaling, Metabolism and Aging, Medical University of Graz, Graz, Austria.
Klaus Zorn-PaulyGottfried Schatz Research Center for Cell Signaling, Metabolism and Aging, Medical University of Graz, Graz, Austria.
Helmut AhammerGottfried Schatz Research Center for Cell Signaling, Metabolism and Aging, Medical University of Graz, Graz, Austria.
Andreas ProkeschGottfried Schatz Research Center for Cell Signaling, Metabolism and Aging, Medical University of Graz, Graz, Austria.
Stefanie StanzerDivision of Oncology, Department of Internal Medicine, Medical University of Graz, Graz, Austria.
Trevor T J DevaneyGottfried Schatz Research Center for Cell Signaling, Metabolism and Aging, Medical University of Graz, Graz, Austria.
Kurt SchmidtInstitute of Pharmaceutical Sciences, Karl Franzens University of Graz, Graz, Austria.
Stephan W JahnDiagnostic & Research Institute of Pathology, Medical University of Graz, Graz, Austria.
Ruth PrasslGottfried Schatz Research Center for Cell Signaling, Metabolism and Aging, Medical University of Graz, Graz, Austria.
Thomas BauernhoferDivision of Oncology, Department of Internal Medicine, Medical University of Graz, Graz, Austria.
Wolfgang SchreibmayerGottfried Schatz Research Center for Cell Signaling, Metabolism and Aging, Medical University of Graz, Graz, Austria. W.Schreibmayer@gmx.at.
Medical University of Graz · ATGraz University of Technology · ATRudjer Boskovic Institute · HRUniversity of Graz · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Excessive expression of subunit 1 of GIRK1 in ER

Indexed as

Breast NeoplasmsCarcinogenesisCell MovementFemaleGene Expression Regulation, NeoplasticG Protein-Coupled Inwardly-Rectifying Potassium ChannelsHumansLymphatic MetastasisMammary Glands, HumanMCF-7 CellsNeoplasmsTranscriptomeG Protein-Coupled Inwardly-Rectifying Potassium Channels

Identifiers

PMID31848385
PMCPMC6917815
OpenAlexW2995741511

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.