Evidence map›Paper›PMID 31848282›Full record

ArticlemBio2019

Antibody-Dependent Cellular Cytotoxicity-Competent Antibodies against HIV-1-Infected Cells in Plasma from HIV-Infected Subjects.

Franck P Dupuy, Sanket Kant, Alexandre Barbé, Jean-Pierre Routy, Julie Bruneau, Bertrand Lebouché, Cécile Tremblay, Marzena Pazgier, Andrés Finzi, Nicole F Bernard

Open access · goldAbstract read
In one paragraph

Article in mBio, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Franck P DupuyResearch Institute of the McGill University Health Centre (RI-MUHC), Montreal, Quebec, Canada.
Sanket KantResearch Institute of the McGill University Health Centre (RI-MUHC), Montreal, Quebec, Canada.
Alexandre BarbéResearch Institute of the McGill University Health Centre (RI-MUHC), Montreal, Quebec, Canada.
Jean-Pierre RoutyResearch Institute of the McGill University Health Centre (RI-MUHC), Montreal, Quebec, Canada.
Julie BruneauDepartment of Family Medicine, Université de Montréal, Montreal, Quebec, Canada.
Bertrand LebouchéResearch Institute of the McGill University Health Centre (RI-MUHC), Montreal, Quebec, Canada.
Cécile TremblayCentre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montreal, Quebec, Canada.
Marzena PazgierInfectious Diseases Division, Department of Medicine of Uniformed Services, University of the Health Sciences, Bethesda, Maryland, USA.
Andrés FinziCentre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montreal, Quebec, Canada.
Nicole F BernardResearch Institute of the McGill University Health Centre (RI-MUHC), Montreal, Quebec, Canada nicole.bernard@mcgill.ca.
McGill University Health Centre · CAMcGill University · CAUniversité de Montréal · CAUniformed Services University of the Health Sciences · US

Funding

Unlocking Envelope: A New Strategy for a Functional Cure Through Antibody-Dependent Cell-Mediated CytotoxicityR01AI129769 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI PAZGIER, MARZENA ELZBIETA · 2017 to 2021
$2.3M
NIAID NIH HHS R01 AI129769
6 · The paper itself

Abstract

Measuring Envelope (Env)-specific antibody (Ab)-dependent cellular cytotoxicity (ADCC)-competent Abs in HIV

Indexed as

Antibodies, NeutralizingAntibody-Dependent Cell CytotoxicityCD4-Positive T-LymphocytesEnzyme-Linked Immunosorbent AssayEpitopes, T-LymphocyteHIV-1HIV AntibodiesHIV Envelope Protein gp120HIV InfectionsHumansImmunoglobulin GAntibodies, NeutralizingEpitopes, T-LymphocyteHIV AntibodiesHIV Envelope Protein gp120Immunoglobulin GADCCADCC assaybroadly neutralizing antibodiesCD4 binding site antibodiesCD4i antibodiesHIV Envelopeneutralizing antibodies

Identifiers

PMID31848282
PMCPMC6918083
OpenAlexW2995165833

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.