Evidence map›Paper›PMID 31848239›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2020

Retroconversion of estrogens into androgens by bacteria via a cobalamin-mediated methylation.

Po-Hsiang Wang, Yi-Lung Chen, Sean Ting-Shyang Wei, Kan Wu, Tzong-Huei Lee, Tien-Yu Wu, Yin-Ru Chiang

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 1 synthesis or guideline pooled it, 66 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Draft genome sequence ofMicrobiology resource announcements · 2026
    Article
  4. Catabolic Mechanism of 17β-Estradiol inJournal of microbiology and biotechnology · 2026
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Bacterial estrogenesis without oxygen: Wood-Ljungdahl pathway likely contributed to the emergence of estrogens in the biosphere.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Allyl Aryl Ether Cleavage byMicrobiology spectrum · 2022
    Article
  17. Article
  18. Characterization and Degradation Pathways ofInternational journal of environmental research and public health · 2022
    Article
  19. Review
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Po-Hsiang WangBiodiversity Research Center, Academia Sinica, 115 Taipei, Taiwan.
Yi-Lung ChenBiodiversity Research Center, Academia Sinica, 115 Taipei, Taiwan.ORCID 0000-0001-7840-7423
Sean Ting-Shyang WeiBiodiversity Research Center, Academia Sinica, 115 Taipei, Taiwan.ORCID 0000-0003-3783-6429
Kan WuBiodiversity Research Center, Academia Sinica, 115 Taipei, Taiwan.
Tzong-Huei LeeInstitute of Fisheries Science, National Taiwan University, 106 Taipei, Taiwan.
Tien-Yu WuBiodiversity Research Center, Academia Sinica, 115 Taipei, Taiwan.
Yin-Ru ChiangBiodiversity Research Center, Academia Sinica, 115 Taipei, Taiwan; yinru915@gate.sinica.edu.tw.
Biodiversity Research Center, Academia Sinica · TWNational Taiwan University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Steroid estrogens modulate physiology and development of vertebrates. Conversion of C

Indexed as

AndrogensBacterial ProteinsBetaproteobacteriaEstrogensMethyltransferasesVitamin B 12AndrogensBacterial ProteinsEstrogensMethyltransferasesVitamin B 12biocatalysiscobalamin-dependent methyltransferaseestrogensmicrobial metabolismsteroids

Identifiers

PMID31848239
PMCPMC6983444
OpenAlexW2996486106

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.