Evidence map›Paper›PMID 31848224›Full record

ArticleThe Journal of biological chemistry2020

The InsP

Elizabeth A Steidle, Victoria A Morrissette, Kotaro Fujimaki, Lucy Chong, Adam C Resnick, Andrew P Capaldi, Ronda J Rolfes

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 30 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Anti-Prion Systems in Saccharomyces cerevisiae.Journal of neurochemistry · 2025
    Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Biochemistry · 2022
    Article
  13. Review
  14. How Do Yeast Cells Contend with Prions?International journal of molecular sciences · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Elizabeth A SteidleDepartment of Biology, Georgetown University, Washington, D. C. 20057.
Victoria A MorrissetteDepartment of Biology, Georgetown University, Washington, D. C. 20057.
Kotaro FujimakiDepartment of Molecular and Cellular Biology, University of Arizona, Tucson, Arizona 85721.
Lucy ChongDivision of Neurosurgery, Colket Translational Research, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania 19104.
Adam C ResnickDivision of Neurosurgery, Colket Translational Research, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania 19104.
Andrew P CapaldiDepartment of Molecular and Cellular Biology, University of Arizona, Tucson, Arizona 85721.
Ronda J RolfesDepartment of Biology, Georgetown University, Washington, D. C. 20057. Electronic address: rolfesr@georgetown.edu.
Georgetown University · USChildren's Hospital of Philadelphia · USUniversity of Arizona · US

Funding

Dissection of the TORC1 Signaling Network in YeastR01GM097329 · NIGMS · UNIVERSITY OF ARIZONA · PI CAPALDI, ANDREW PAUL · 2011 to 2024
$4.7M
University of Arizona's Initiative for Maximizing Student Development (IMSD)T32GM139779 · NIGMS · UNIVERSITY OF ARIZONA · PI FRANS E TAX · 2022 to 2026
$2.9M
Graduate Training in Biochemistry and Molecular BiologyT32GM136536 · NIGMS · UNIVERSITY OF ARIZONA · PI Andrew Paul Capaldi, FRANS E TAX · 2020 to 2026
$2.4M
NIGMS NIH HHS R01 GM097329NIGMS NIH HHS T32 GM136536NIGMS NIH HHS T32 GM139779
6 · The paper itself

Abstract

The environmental stress response (ESR) is critical for cell survival. Yeast cells unable to synthesize inositol pyrophosphates (PP-InsPs) are unable to induce the ESR. We recently discovered a diphosphoinositol pentakisphosphate (PP-InsP

Indexed as

Cell CycleCell SurvivalDiphosphatesDNA-Binding ProteinsGene Expression Regulation, FungalInositolOsmotic PressureOxidation-ReductionOxidative StressPeptides, CyclicProtein Tyrosine PhosphatasesSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsSignal TransductionStress, PhysiologicalTranscription FactorsCTTHWGFTLC peptideDiphosphatesdiphosphoric acidDNA-Binding ProteinsInositolMSN2 protein, S cerevisiaePeptides, CyclicProtein Tyrosine PhosphatasesSaccharomyces cerevisiae ProteinsSiw14 protein, S cerevisiaeTranscription Factorsgene expressioninositol pyrophosphateMSN2Saccharomyces cerevisiaeSIW14stress responsetranscription regulationyeast genetics

Identifiers

PMID31848224
PMCPMC7029108
OpenAlexW2994723825

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.