Evidence map›Paper›PMID 31848222›Full record

ArticleGenetics2020

An ABCG Transporter Functions in Rab Localization and Lysosome-Related Organelle Biogenesis in

Laura Voss, Olivia K Foster, Logan Harper, Caitlin Morris, Sierra Lavoy, James N Brandt, Kimberly Peloza, Simran Handa, Amanda Maxfield, Marie Harp and 4 more

Open access · greenAbstract read
In one paragraph

Article in Genetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.1field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Lysosome-related organelles contain an expansion compartment that mediates delivery of zinc transporters to promote homeostasis.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Laura VossDepartment of Biology, Lewis & Clark College, Portland, Oregon.ORCID 0000-0002-3572-2447
Olivia K FosterDepartment of Biology, Lewis & Clark College, Portland, Oregon.ORCID 0000-0001-7782-7995
Logan HarperDepartment of Biology, Lewis & Clark College, Portland, Oregon.
Caitlin MorrisDepartment of Biology, Lewis & Clark College, Portland, Oregon.
Sierra LavoyDepartment of Biology, Lewis & Clark College, Portland, Oregon.ORCID 0000-0001-8216-3222
James N BrandtDepartment of Biology, Lewis & Clark College, Portland, Oregon.
Kimberly PelozaDepartment of Biology, Lewis & Clark College, Portland, Oregon.ORCID 0000-0002-8255-5311
Simran HandaDepartment of Biology, Lewis & Clark College, Portland, Oregon.
Amanda MaxfieldDepartment of Biology, Lewis & Clark College, Portland, Oregon.
Marie HarpDepartment of Biology, Lewis & Clark College, Portland, Oregon.
Brian KingDepartment of Biology, Lewis & Clark College, Portland, Oregon.
Victoria EichtenDepartment of Biology, Lewis & Clark College, Portland, Oregon.
Fiona M RamboDepartment of Biology, Lewis & Clark College, Portland, Oregon.
Greg J HermannDepartment of Biology, Lewis & Clark College, Portland, Oregon hermann@lclark.edu.ORCID 0000-0002-0278-6356
Lewis & Clark College · US

Funding

Rab activation by ABC proteins during lysosome-related organelle biogenesisR15GM120639 · NIGMS · LEWIS AND CLARK COLLEGE · PI HERMANN, GREG J · 2016 to 2016
$383k
NIGMS NIH HHS R15 GM120639
6 · The paper itself

Abstract

ABC transporters couple ATP hydrolysis to the transport of substrates across cellular membranes. This protein superfamily has diverse activities resulting from differences in their cargo and subcellular localization. Our work investigates the role of the ABCG family member WHT-2 in the biogenesis of gut granules, a

Indexed as

AnimalsATP-Binding Cassette TransportersATP Binding Cassette Transporter, Subfamily GATP Binding Cassette Transporter, Subfamily G, Member 2Caenorhabditis elegansCaenorhabditis elegans ProteinsCytoplasmic GranulesEndosomesLysosomesMembrane Transport ProteinsMutationOrganelle BiogenesisPhenotypeProtein Transportrab GTP-Binding ProteinsVesicular Transport ProteinsATP-Binding Cassette TransportersATP Binding Cassette Transporter, Subfamily GATP Binding Cassette Transporter, Subfamily G, Member 2Caenorhabditis elegans ProteinsMembrane Transport Proteinsrab GTP-Binding ProteinsVesicular Transport ProteinsABC transporterCaenorhabditis eleganslysosome-related organellemembrane traffickingRab GTPase

Identifiers

PMID31848222
PMCPMC7017009
OpenAlexW2994853715

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.