ArticleJournal of neurointerventional surgery2020
Aneurysm characteristics, coil packing, and post-coiling hemodynamics affect long-term treatment outcome.
Article in Journal of neurointerventional surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.
- Risk Factors for Recurrence of Intracranial Aneurysm After Coil Embolization: A Meta-Analysis.Frontiers in neurology · 2022Pooled it
- Trial
- Predictive simulation of coil mechanics uncovers shape-driven determinants of endovascular coiling efficacy in intracranial aneurysms.APL bioengineering · 2026Article
- Predicting Cerebral Aneurysm Recurrence after Coil Embolization: A Novel Deep Learning Approach Using Time-of-flight Magnetic Resonance Angiography.Neurologia medico-chirurgica · 2026Article
- Microsurgical clipping for coil-extruded recurrent aneurysms: Case series and technical pearls.Surgical neurology international · 2026Article
- Delayed posterior tilting of a giant basilar tip aneurysm following stent-assisted coiling with therapeutic P1 occlusion: A case report.Surgical neurology international · 2026Article
- Earlier and greater vascular endothelial cell proliferation on hydrocoils compared to bare platinum coils: an in vitro study.Scientific reports · 2025Article
- Deployment techniques and crossability of the EVO stent in wide-neck bifurcation aneurysms: AnInterventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025Article
- Imaging of Intracranial Aneurysms: A Review of Standard and Advanced Imaging Techniques.Translational stroke research · 2025Review
- A novel neutrophil extracellular traps related diagnostic signature for intracranial aneurysm.BMC neurology · 2025Article
- Exploration of the effect of morphology and location on hemodynamics of small aneurysms: a variable-controlled study based on two cases with tandem aneurysms.Biomedical engineering online · 2025Article
- Article
- Standardized viscosity as a source of error in computational fluid dynamic simulations of cerebral aneurysms.Medical physics · 2024Article
- Mid-term safety and efficacy in small intracranial aneurysm coiling: results from TARGETFrontiers in neurology · 2024Article
- Experimental study using phantom models of cerebral aneurysms and 4D-DSA to measure blood flow on 3D-color-coded images.Technology and health care : official journal of the European Society for Engineering and Medicine · 2024Article
- Improving the accuracy of computational fluid dynamics simulations of coiled cerebral aneurysms using finite element modeling.Journal of biomechanics · 2023Article
- Safety and efficacy of endovascular treatment for tiny ruptured intracranial aneurysms with low-profile visualized intraluminal support stents.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2023Article
- An attention residual u-net with differential preprocessing and geometric postprocessing: Learning how to segment vasculature including intracranial aneurysms.Medical image analysis · 2023Article
- Development and assessment of machine learning models for predicting recurrence risk after endovascular treatment in patients with intracranial aneurysms.Neurosurgical review · 2022Article
- Transcriptome-Based Dissection of Intracranial Aneurysms Unveils an "Immuno-Thermal" Microenvironment and Defines a Pathological Feature-Derived Gene Signature for Risk Estimation.Frontiers in immunology · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 1 institution in 1 country.
Funding
Abstract
backgroundRecurrence of intracranial aneurysms after endovascular coiling is a serious clinical concern.
objectiveWe hypothesized that recurrence is associated with aneurysm morphology and flow, as well as the coil intervention and the induced flow modifications.
methodsWe collected 52 primary-coiling aneurysm cases that were either occluded (n=34) or recurrent (n=18) at >1 year follow-up. We created aneurysm models from pre-coiling digital subtraction angiographic images, calculated aneurysm morphology, simulated pre-coiling hemodynamics, modeled coil deployment, and obtained post-coiling hemodynamics for each case. We performed univariable analysis on 26 morphologic, treatment-specific, and hemodynamic parameters to distinguish between recurrent and occluded groups, and multivariable analysis to identify independently significant parameters associated with recurrence. Univariable analysis was also performed on ruptured and unruptured aneurysm subcohorts separately to investigate if they shared specific significant parameters.
resultsRecurrence was associated with pre-coiling aneurysm morphologic and flow parameters including larger size (maximum dimension and volume), larger neck (diameter, area, and neck-to-parent-artery ratio), and higher flow momentum and kinetic energy. Recurrence was also associated with lower coil packing (packing density and uncoiled volume), higher post-treatment flow (velocity, momentum, and kinetic energy), lower post-treatment washout time, and higher post-treatment impingement force at the neck. Multivariable analysis identified two aneurysmal characteristics (neck diameter and pre-coiling flow kinetic energy), one coil packing parameter (uncoiled volume), and one post-treatment hemodynamic parameter (flow momentum) that were independently associated with recurrence. In ruptured aneurysms, recurrence was associated with larger neck (diameter and area), whereas in unruptured aneurysms, recurrence was associated with larger size (maximum dimension and volume). In both subcohorts, recurrence was associated with higher post-coiling flow momentum and kinetic energy.
conclusionRecurrence at >1 year after coil treatment is associated with intrinsic aneurysm characteristics, coiling itself, and flow changes induced by coiling. Larger aneurysm size and neck, less coil packing, and higher intra-aneurysmal flow before and after coiling predict recurrence.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.