Evidence map›Paper›PMID 31847543›Full record

ReviewAntioxidants & redox signaling2020

2-Hydroxyglutarate in Cancer Cells.

Petr Ježek

Open access · hybridAbstract readReview
In one paragraph

Review in Antioxidants & redox signaling, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 85 papers.

0numbers the graph read from it
0cells of the map it votes in
85citing papers in PubMed
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

85 citing papers in PubMed, 121 citations in OpenAlex.

  1. LDH isozymes as targets for cancer therapy.Journal of enzyme inhibition and medicinal chemistry · 2026
    Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. State of the Art of IDH Inhibitors: Emerging Questions and Perspectives.Anti-cancer agents in medicinal chemistry · 2026
    Review
  7. Review
  8. Review
  9. Review
  10. Alzheimer's disease risk geneBrain communications · 2026
    Article
  11. Evaluation of Anticancer Potential ofAntioxidants (Basel, Switzerland) · 2025
    Article
  12. Article
  13. Article
  14. Article
  15. Evolutionary Transcriptomics of Cancer Development.International journal of molecular sciences · 2025
    Article
  16. Article
  17. Review
  18. Abnormal changes in metabolites caused by mJournal of advanced research · 2025
    Review
  19. Review
  20. MiCK: a database of gut microbial genes linked with chemoresistance in cancer patients.Database : the journal of biological databases and curation · 2024
    Article

25 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Petr JežekDepartment of Mitochondrial Physiology, Institute of Physiology of the Czech Academy of Sciences, Prague, Czech Republic.
Czech Academy of Sciences · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Disease SusceptibilityAnimalsDisease ProgressionEnergy MetabolismEpigenesis, GeneticGene Expression Regulation, NeoplasticGlutaratesHumansImmunomodulationIsocitrate DehydrogenaseMutationNeoplasmsNeoplastic Stem CellsOxidation-ReductionSignal Transductionalpha-hydroxyglutarateGlutaratesIDH1 protein, humanIDH2 protein, humanIsocitrate Dehydrogenase2-hydroxyglutarateDNA and histone hypermethylationimmune systemisocitrate dehydrogenase 1 and 2metabolic markermetabolic reprogramming in cancertumor cross talk

Identifiers

PMID31847543
PMCPMC7533892
OpenAlexW2995984012

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.