Evidence map›Paper›PMID 31847375›Full record

ArticleInternational journal of molecular sciences2019

Changes in Adipose Tissue Distribution and Association between Uric Acid and Bone Health during Menopause Transition.

Gloria Bonaccorsi, Alessandro Trentini, Pantaleo Greco, Veronica Tisato, Donato Gemmati, Nicoletta Bianchi, Melchiore Giganti, Maurizio Rossini, Giuseppe Guglielmi, Carlo Cervellati

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Gloria BonaccorsiDepartment of Morphology, Surgery and Experimental Medicine, University of Ferrara, 44124 Ferrara, Italy.ORCID 0000-0001-5005-0274
Alessandro TrentiniDepartment of Biomedical and Specialist Surgical Sciences, Section of Medical Biochemistry, Molecular Biology and Genetics, University of Ferrara, 44121 Ferrara, Italy.ORCID 0000-0003-3579-7921
Pantaleo GrecoDepartment of Morphology, Surgery and Experimental Medicine, University of Ferrara, 44124 Ferrara, Italy.
Veronica TisatoDepartment of Morphology, Surgery and Experimental Medicine, and LTTA Centre, University of Ferrara, 44121 Ferrara, Italy.ORCID 0000-0001-8448-066X
Donato GemmatiCenter of Gender Medicine, University of Ferrara, 44121 Ferrara, Italy.
Nicoletta BianchiDepartment of Biomedical and Specialist Surgical Sciences, Section of Medical Biochemistry, Molecular Biology and Genetics, University of Ferrara, 44121 Ferrara, Italy.ORCID 0000-0001-9280-6017
Melchiore GigantiDepartment of Morphology, Surgery and Experimental Medicine, University of Ferrara, 44124 Ferrara, Italy.
Maurizio RossiniRheumatology Unit, Department of Medicine, University of Verona, 37134 Verona, Italy.ORCID 0000-0001-9692-2293
Giuseppe GuglielmiDepartment of Clinical and Experimental Medicine, Foggia University School of Medicine, 71121 Foggia, Italy.ORCID 0000-0002-4325-8330
Carlo CervellatiMenopause and Osteoporosis Centre, University of Ferrara, 44124 Ferrara, Italy.ORCID 0000-0003-4777-6300
University of Ferrara · ITUniversity of Foggia · ITUniversity of Verona · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite convincing experimental evidence, epidemiological studies on the effects of serum uric acid (SUA) on bone health are still conflicting since factors influencing SUA bioavailability have not been adequately considered. To shed some light on this issue, we investigated the impact of adiposity and menopause status on the relationship between SUA and bone health. We examined SUA in relation to bone mineral density (BMD) at different skeletal sites and with markers of bone metabolism in 124 pre-menopausal and 234 post-menopausal women and assessed whether adiposity, evaluated by anthropometry and dual x-ray absorptiometry (DXA), might have a discriminant role. After conservative adjustment (covariates: age, hormones treatment, smoking and time since menopause), SUA showed a significant and positive association with total hip BMD (

Indexed as

Absorptiometry, PhotonAdipose TissueAdiposityAdultBiological AvailabilityBody Mass IndexBone and BonesBone DensityFemaleHumansMiddle AgedPostmenopausePremenopauseRetrospective StudiesTissue DistributionUric AcidUric Acidandroid fat distributionbody fat massmenopause transitionpurine metabolismuric acid

Identifiers

PMID31847375
PMCPMC6941025
OpenAlexW2995291905

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.