Evidence map›Paper›PMID 31847344›Full record

ArticleJournal of clinical medicine2019

Impact of Positive Airway Pressure on International Restless Legs Syndrome Score in Sleep Disordered Breathing.

Seetha Lakshmanan, Nicolas R Thompson, Maeve Pascoe, Reena Mehra, Nancy Foldvary-Schaefer, Irene L Katzan, Harneet K Walia

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. International Consensus Statement on Obstructive Sleep Apnea.International forum of allergy & rhinology · 2023
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Seetha LakshmananSleep Disorders Center, Neurological Institute, Cleveland Clinic, Cleveland, OH 44195, USA.
Nicolas R ThompsonDepartment of Qualitative Health Sciences, Cleveland Clinic, Cleveland, OH 44195, USA.ORCID 0000-0002-8973-5219
Maeve PascoeSleep Disorders Center, Neurological Institute, Cleveland Clinic, Cleveland, OH 44195, USA.
Reena MehraSleep Disorders Center, Neurological Institute, Cleveland Clinic, Cleveland, OH 44195, USA.
Nancy Foldvary-SchaeferSleep Disorders Center, Neurological Institute, Cleveland Clinic, Cleveland, OH 44195, USA.
Irene L KatzanNeurological Institute Center of Research Outcomes, Cleveland Clinic, Cleveland, OH 44195, USA.
Harneet K WaliaSleep Disorders Center, Neurological Institute, Cleveland Clinic, Cleveland, OH 44195, USA.
Cleveland Clinic · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

objectiveStudies have shown increased prevalence of restless legs syndrome (RLS) in sleep disordered breathing (SDB), however limited data have focused on the impact of SDB therapy on RLS. We hypothesize that positive airway pressure (PAP) will improve the International Restless Legs Syndrome (IRLS) score among SDB patients compared to patients without PAP.

methodsPatients with AHI ≥ 5 who responded positively to a RLS qualifier question from January 2010 to May 2015 were included in this retrospective study. IRLS score was used to measure RLS symptom severity. Two-sample

resultsIn 434 patients (51.9 ± 13.4years, 50.5% female, 77.6% Caucasian; 325 PAP, 109 control), IRLS scores improved from baseline to follow-up, with the PAP group achieving significant improvement after adjustment for covariates (difference in IRLS: -1.8 (CI -3.6,0.00),

conclusionsAmong SDB patients with a positive RLS qualifier, those who used PAP therapy achieved significantly greater improvement in IRLS scores than patients who did not use PAP, with more significant changes in the PAP adherent group. This is the first large clinical study to examine these relationships, providing a basis for future prospective interventional trials and informing clinicians of expected improvement in IRLS score in PAP treated SDB populations.

Indexed as

International Restless Legs Syndrome score (IRLS)positive airway pressure (PAP)restless legs syndrome (RLS)sleep disordered breathing (SDB)

Identifiers

PMID31847344
PMCPMC6947176
OpenAlexW2995561512

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.