ArticlePolymers2019
Dual Crosslinked Collagen/Chitosan Film for Potential Biomedical Applications.
Article in Polymers, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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The trial behind it
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Who cites it
31 citing papers in PubMed.
- Chitosan-Based Hydrogels in Vascular Tissue Engineering Applications.Materials (Basel, Switzerland) · 2026Review
- Adhesive bioactive materials in ocular applications: Toward smart, regenerative, and minimally invasive therapies.Bioactive materials · 2026Review
- Enhanced Properties of Collagen Nanofiber Scaffolds via Chitosan/Polypyrrole/Glutaraldehyde Double-Crosslinking.Membranes · 2026Article
- Beyond Reinforcement: Collagen-Inorganic Composites as a Roadmap for Next-Generation Biomaterials.ACS materials Au · 2026Review
- Enhancing Thin Film Properties of Chitosan-Collagen Biocomposites Through Potassium Silicate and Tannic Acid Integration.Polymers · 2025Article
- Multiple-Layer Chitosan-Based Patches Medicated With LTX-109 Antimicrobial Peptide for Modulated Local Therapy in the Management of Chronic Wounds.Macromolecular bioscience · 2025Article
- Chitosan based extruded nanofibrous bioscaffold for local delivery of mesenchymal stem cells to improve diabetic wound healing.Stem cell research & therapy · 2024Article
- Enabling 3D bioprinting of cell-laden pure collagen scaffolds via tannic acid supporting bath.Frontiers in bioengineering and biotechnology · 2024Article
- Collagen-Based Hydrogels for Cartilage Regeneration.Orthopaedic surgery · 2023Review
- Biomimetic Bilayered Scaffolds for Tissue Engineering: From Current Design Strategies to Medical Applications.Advanced healthcare materials · 2023Review
- Technological Aspects and Evaluation Methods for Polymer Matrices as Dental Drug Carriers.Biomedicines · 2023Review
- Self-Standing Bioinspired Polymer Films Doped with Ultrafine Silver Nanoparticles as Innovative Antimicrobial Material.International journal of molecular sciences · 2022Article
- Advanced Optical Wavefront Technologies to Improve Patient Quality of Vision and Meet Clinical Requests.Polymers · 2022Review
- Collagen as a Biomaterial for Skin and Corneal Wound Healing.Journal of functional biomaterials · 2022Review
- Recent Advances of Chitosan Formulations in Biomedical Applications.International journal of molecular sciences · 2022Review
- Preparation and Properties of Blended Composite Film Manufactured Using Walnut-Peptide-Chitosan-Sodium Alginate.Foods (Basel, Switzerland) · 2022Article
- Characterization and Cytocompatibility of Collagen-Gelatin-Elastin (CollaGee) Acellular Skin Substitute towards Human Dermal Fibroblasts: In Vitro Assessment.Biomedicines · 2022Article
- Review
- Genipin-Crosslinking Effects on Biomatrix Development for Cutaneous Wound Healing: A Concise Review.Frontiers in bioengineering and biotechnology · 2022Review
- Numerical Study of Customized Artificial Cornea Shape by Hydrogel Biomaterials on Imaging and Wavefront Aberration.Polymers · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The application of polymeric biomaterial scaffolds utilizing crosslinking strategy has become an effective approach in these days. In the present study, the development and characterization of collagen-chitosan hydrogel film has been reported on using dual crosslinking agent's, i.e., tannic acid and genipin simultaneously. Incorporation of genipin imparts a greenish-blue color to the polymeric film. The effect of dual crosslinking and their successful interaction within the matrix was evaluated by infrared analysis spectroscopy. The porosity of the film was examined using scanning electron microscopy (SEM). Results of TGA determine the intermediate thermal degradation. Further, the crosslinking phenomenon has found primary impact on the strength of the films. Enzymatic degradation for the films was performed with lysozyme and lipase. The cell adhesion and proliferation was also accomplished using mouse embryonic cell lines wherein the cells cultured on the dual crosslinked film. The thriving utilization of such dual crosslinked polymeric film finds their applications in ophthalmology especially as an implant for temporary injured cornea and skin tissue regeneration.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.