Evidence map›Paper›PMID 31847200›Full record

ArticleInternational journal of molecular sciences2019

Reductive Activity and Mechanism of Hypoxia- Targeted AGT Inhibitors: An Experimental and Theoretical Investigation.

Weinan Xiao, Guohui Sun, Tengjiao Fan, Junjun Liu, Na Zhang, Lijiao Zhao, Rugang Zhong

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Weinan XiaoBeijing Key Laboratory of Environmental & Viral Oncology, College of Life Science and Bioengineering, Beijing University of Technology, Beijing 100124, China.
Guohui SunBeijing Key Laboratory of Environmental & Viral Oncology, College of Life Science and Bioengineering, Beijing University of Technology, Beijing 100124, China.ORCID 0000-0003-2259-5431
Tengjiao FanBeijing Key Laboratory of Environmental & Viral Oncology, College of Life Science and Bioengineering, Beijing University of Technology, Beijing 100124, China.
Junjun LiuBeijing Key Laboratory of Environmental & Viral Oncology, College of Life Science and Bioengineering, Beijing University of Technology, Beijing 100124, China.
Na ZhangBeijing Key Laboratory of Environmental & Viral Oncology, College of Life Science and Bioengineering, Beijing University of Technology, Beijing 100124, China.
Lijiao ZhaoBeijing Key Laboratory of Environmental & Viral Oncology, College of Life Science and Bioengineering, Beijing University of Technology, Beijing 100124, China.ORCID 0000-0002-4876-323X
Rugang ZhongBeijing Key Laboratory of Environmental & Viral Oncology, College of Life Science and Bioengineering, Beijing University of Technology, Beijing 100124, China.
Beijing University of Technology · CN

Funding

Beijing Natural Science Foundation 7184192Beijing Postdoctoral Research Foundation 2018-ZZ-022Chaoyang District Postdoctoral Research Foundation 2018ZZ-01-25China Postdoctoral Science Foundation 2017M620567Education Commission Science and Technology Project of Beijing Municipality PXM2015_014204_500175National Natural Science Foundation of China 21778011the Great Wall Scholars Program of Beijing Municipal Education Commission CIT&TCD20180308
6 · The paper itself

Abstract

O

Indexed as

Drug Delivery SystemsMolecular Docking SimulationO(6)-Methylguanine-DNA MethyltransferaseChromatography, High Pressure LiquidEnzyme InhibitorsHumansHypoxiaProdrugsTandem Mass SpectrometryEnzyme InhibitorsO(6)-Methylguanine-DNA MethyltransferaseProdrugsdensity functional theoryHPLC-ESI-MS/MShypoxia-activated AGT inhibitorsmolecular dockingreduction of nitro grouptumor targeting

Identifiers

PMID31847200
PMCPMC6941096
OpenAlexW2995168828

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.