Evidence map›Paper›PMID 31847196›Full record

ReviewPlants (Basel, Switzerland)2019

Development of Improved Fruit, Vegetable, and Ornamental Crops Using the CRISPR/Cas9 Genome Editing Technique.

Lígia Erpen-Dalla Corte, Lamiaa M Mahmoud, Tatiana S Moraes, Zhonglin Mou, Jude W Grosser, Manjul Dutt

Open access · goldAbstract readReview
In one paragraph

Review in Plants (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 84 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. CRISPR-Cas Gene Editing Technology in Potato.International journal of molecular sciences · 2025
    Review
  4. Review
  5. Article
  6. CRISPR/Cas as a Genome-Editing Technique in Fruit Tree Breeding.International journal of molecular sciences · 2023
    Review
  7. Review
  8. Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Establishment of a Novel and EfficientPlants (Basel, Switzerland) · 2021
    Article
  16. Review
  17. Review
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 3 countries.

Lígia Erpen-Dalla CorteDepartment of Agronomy, Universidade Estadual de Londrina, Londrina 86057-970, PR, Brazil.ORCID 0000-0002-0226-3520
Lamiaa M MahmoudPomology Department, Faculty of Agriculture, Mansoura University, 35516 Mansoura, Egypt.
Tatiana S MoraesCentro de Energia Nuclear na Agricultura, Universidade de São Paulo, Piracicaba 13416-000, SP, Brazil.
Zhonglin MouDepartment of Microbiology and Cell Sciences, University of Florida, Gainesville, FL 32603, USA.
Jude W GrosserCitrus Research and Education Center, University of Florida, Lake Alfred, FL 33850, USA.
Manjul DuttCitrus Research and Education Center, University of Florida, Lake Alfred, FL 33850, USA.ORCID 0000-0002-8027-7012
Florida Department of Citrus · USMansoura University · EGUniversidade de São Paulo · BRUniversidade Estadual de Londrina · BRUniversity of Florida · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Horticultural crops, including fruit, vegetable, and ornamental plants are an important component of the agriculture production systems and play an important role in sustaining human life. With a steady growth in the world's population and the consequent need for more food, sustainable and increased fruit and vegetable crop production is a major challenge to guarantee future food security. Although conventional breeding techniques have significantly contributed to the development of important varieties, new approaches are required to further improve horticultural crop production. Clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein 9 (Cas9) has emerged as a valuable genome-editing tool able to change DNA sequences at precisely chosen loci. The CRISPR/Cas9 system was developed based on the bacterial adaptive immune system and comprises of an endonuclease guided by one or more single-guide RNAs to generate double-strand breaks. These breaks can then be repaired by the natural cellular repair mechanisms, during which genetic mutations are introduced. In a short time, the CRISPR/Cas9 system has become a popular genome-editing technique, with numerous examples of gene mutation and transcriptional regulation control in both model and crop plants. In this review, various aspects of the CRISPR/Cas9 system are explored, including a general presentation of the function of the CRISPR/Cas9 system in bacteria and its practical application as a biotechnological tool for editing plant genomes, particularly in horticultural crops.

Indexed as

CRISPR/Cas9gene knockoutgenome editinghorticultural plantsprecision editing

Identifiers

PMID31847196
PMCPMC6963220
OpenAlexW2996506795

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.