Evidence map›Paper›PMID 31847119›Full record

ArticleInternational journal of molecular sciences2019

Antibacterial, Antibiofilm, and Antiadhesive Properties of Different Quaternized Chitosan Derivatives.

Anna Maria Piras, Semih Esin, Arianna Benedetti, Giuseppantonio Maisetta, Angela Fabiano, Ylenia Zambito, Giovanna Batoni

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 54 citations in OpenAlex.

  1. Bioactive Coatings with Antimicrobial Activity fromMolecules (Basel, Switzerland) · 2026
    Review
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  20. Planktonic and Biofilm-AssociatedMicroorganisms · 2021
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Anna Maria PirasDepartment of Pharmacy, University of Pisa, 56126 Pisa, Italy.ORCID 0000-0002-4082-6400
Semih EsinDepartment of Translational Research and New technologies in Medicine and Surgery, University of Pisa, 56126 Pisa, Italy.ORCID 0000-0002-4358-5294
Arianna BenedettiDepartment of Translational Research and New technologies in Medicine and Surgery, University of Pisa, 56126 Pisa, Italy.
Giuseppantonio MaisettaDepartment of Translational Research and New technologies in Medicine and Surgery, University of Pisa, 56126 Pisa, Italy.
Angela FabianoDepartment of Pharmacy, University of Pisa, 56126 Pisa, Italy.
Ylenia ZambitoDepartment of Pharmacy, University of Pisa, 56126 Pisa, Italy.ORCID 0000-0003-0064-233X
Giovanna BatoniDepartment of Translational Research and New technologies in Medicine and Surgery, University of Pisa, 56126 Pisa, Italy.
University of Pisa · IT

Funding

University of Pisa PRA 2017_18 and PRA 2018_18
6 · The paper itself

Abstract

In the era of antimicrobial resistance, the identification of new antimicrobials is a research priority at the global level. In this regard, the attention towards functional antimicrobial polymers, with biomedical/pharmaceutical grade, and exerting anti-infective properties has recently grown. The aim of this study was to evaluate the antibacterial, antibiofilm, and antiadhesive properties of a number of quaternized chitosan derivatives that have displayed significant muco-adhesive properties and wound healing promotion features in previous studies. Low (QAL) and high (QAH) molecular weight quaternized chitosan derivatives were synthetized and further modified with thiol moieties or pendant cyclodextrin, and their antibacterial activity evaluated as minimal inhibitory concentrations (MIC) and minimal bactericidal concentrations (MBC). The ability of the derivatives to prevent biofilm formation was assessed by crystal violet staining. Both QAL and QAH derivatives exerted a bactericidal and/or inhibitory activity on the growth of

Indexed as

Anti-Bacterial AgentsChitosanCoated Materials, BiocompatibleTitaniumBacterial AdhesionBiofilmsPseudomonas aeruginosaStaphylococcus epidermidisAnti-Bacterial AgentsChitosanCoated Materials, BiocompatibleTitaniumantibiofilmbacteria adhesionchitosanchitosan derivativesfunctionalized titaniumimplant-associated infectionquaternized chitosan

Identifiers

PMID31847119
PMCPMC6940869
OpenAlexW2994778999

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.