Evidence map›Paper›PMID 31847089›Full record

ArticleMolecules (Basel, Switzerland)2019

Synergistic Inhibition of Acetylcholinesterase by Alkaloids Derived from Stephaniae Tetrandrae Radix, Coptidis Rhizoma and Phellodendri Chinensis Cortex.

Xiang-Peng Kong, Etta Y L Liu, Zhi-Cong Chen, Miranda Li Xu, Anna X D Yu, Qi-Yun Wu, Ying-Jie Xia, Ran Duan, Tina T X Dong, Karl W K Tsim

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 38 citations in OpenAlex.

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  6. Role of medicinal plants in inhibiting SARS-CoV-2 and in the management of post-COVID-19 complications.Phytomedicine : international journal of phytotherapy and phytopharmacology · 2022
    Article
  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Xiang-Peng KongShenzhen Key Laboratory of Edible and Medicinal Bioresources, HKUST Shenzhen Research Institute, Hi-Tech Park, Shenzhen 518057, China.
Etta Y L LiuShenzhen Key Laboratory of Edible and Medicinal Bioresources, HKUST Shenzhen Research Institute, Hi-Tech Park, Shenzhen 518057, China.
Zhi-Cong ChenShenzhen Key Laboratory of Edible and Medicinal Bioresources, HKUST Shenzhen Research Institute, Hi-Tech Park, Shenzhen 518057, China.
Miranda Li XuShenzhen Key Laboratory of Edible and Medicinal Bioresources, HKUST Shenzhen Research Institute, Hi-Tech Park, Shenzhen 518057, China.
Anna X D YuShenzhen Key Laboratory of Edible and Medicinal Bioresources, HKUST Shenzhen Research Institute, Hi-Tech Park, Shenzhen 518057, China.
Qi-Yun WuShenzhen Key Laboratory of Edible and Medicinal Bioresources, HKUST Shenzhen Research Institute, Hi-Tech Park, Shenzhen 518057, China.
Ying-Jie XiaShenzhen Key Laboratory of Edible and Medicinal Bioresources, HKUST Shenzhen Research Institute, Hi-Tech Park, Shenzhen 518057, China.
Ran DuanShenzhen Key Laboratory of Edible and Medicinal Bioresources, HKUST Shenzhen Research Institute, Hi-Tech Park, Shenzhen 518057, China.
Tina T X DongShenzhen Key Laboratory of Edible and Medicinal Bioresources, HKUST Shenzhen Research Institute, Hi-Tech Park, Shenzhen 518057, China.
Karl W K TsimShenzhen Key Laboratory of Edible and Medicinal Bioresources, HKUST Shenzhen Research Institute, Hi-Tech Park, Shenzhen 518057, China.
Hong Kong University of Science and Technology · HKShanxi University · CN

Funding

China Postdoctoral Science Foundation 2019M653087Science, Technology and Innovation Commission of Shenzhen Municipality JCYJ20160229205812004Science, Technology and Innovation Commission of Shenzhen Municipality JCYJ20170413173747440Science, Technology and Innovation Commission of Shenzhen Municipality ZDSYS201707281432317
6 · The paper itself

Abstract

Alkaloids having acetylcholinesterase (AChE) inhibitory activity are commonly found in traditional Chinese medicine (TCM); for example, berberine from

Indexed as

AcetylcholinesteraseAlkaloidsBenzylisoquinolinesBerberineCholinesterase InhibitorsCoptis chinensisDrug CombinationsDrugs, Chinese HerbalDrug SynergismMedicine, Chinese TraditionalMolecular Docking SimulationPhellodendronPlant ExtractsStephania tetrandraAcetylcholinesteraseAlkaloidsBenzylisoquinolinesBerberineCholinesterase InhibitorsCoptidis rhizoma extractcoptisineDrug CombinationsDrugs, Chinese HerbalfangchinolinePlant Extractsacetylcholinesteraseberberinecoptisinefangchinolinesynergistic effect

Identifiers

PMID31847089
PMCPMC6943709
OpenAlexW2995558565

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.