ArticleThe journal of international advanced otology2019
Analysis of the Microbiome in the Adenoids of Korean Children with Otitis Media with Effusion.
Article in The journal of international advanced otology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 20 citations in OpenAlex.
- Molecular Characterization of the Middle Ear Microbiome in Pediatric Otitis Media with Effusion: Diagnostic and Clinical Implications.Journal of clinical medicine · 2026Review
- Salivary microbiota composition and caries status in children with hearing impairment: a cross-sectional comparative study.Clinical oral investigations · 2026Article
- Dysbiosis and Links of the Middle Ear, Nasal, and Oral Microbiota in Chronic Otitis Media with Effusion.MedComm · 2025Article
- Article
- The association between the adenoid microbiome and chronic otitis media with effusion in children differs according to age.Frontiers in cellular and infection microbiology · 2025Article
- Identifying the Microbiome of the Adenoid Surface of Children Suffering from Otitis Media with Effusion and Children without Middle Ear Effusion Using 16S rRNA Genetic Sequencing.Microorganisms · 2023Article
- Associations of Microbial Diversity with Age and Other Clinical Variables among Pediatric Chronic Rhinosinusitis (CRS) Patients.Microorganisms · 2023Article
- An Overview of Adenoid Microbiome Using 16S rRNA Gene Sequencing-Based Metagenomic Analysis.Medicina (Kaunas, Lithuania) · 2022Article
- Profiling the Human Oral Mycobiome in Tissue and Saliva Using ITS2 DNA Metabarcoding Compared to a Fungal-Specific Database.Methods in molecular biology (Clifton, N.J.) · 2021Article
- Review of otitis media microbiome studies: What do they tell us?Laryngoscope investigative otolaryngology · 2020Review
- Upper Respiratory Tract Microbiome and Otitis Media Intertalk: Lessons from the Literature.Journal of clinical medicine · 2020Review
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe adenoid pad, which is located between the orifice of the Eustachian tube (ET) and posterior nasal cavity, can affect the development of otitis media with effusion (OME) because of its anatomical location. The aim of the present study was to evaluate adenoid microbial colonization through 16S ribosomal RNA (rRNA) pyrosequencing, an advanced molecular technique, and to document the relationship with OME. MATERIALS AND
methodsAdenoid samples were collected using sterile cotton from 32 children during ventilation tube insertion. Sixteen children with OME who underwent tonsillectomy and adenoidectomy due to obstructive symptoms were assigned to the OME group and sixteen children without OME were assigned to the control group. We performed a 16S rRNA-based culture-independent survey of bacterial communities using the MiSeq platform.
resultsThe diversity index, mean operational taxonomic units, and Shannon index were lower in the OME group than those in the control group. A taxonomic analysis showed differences in microbiota distribution between the OME and control groups at the phylum, genus, and species levels. The analysis, which was based on weighted UniFrac distances, revealed differences in microbial composition between the two groups.
conclusionBacterial community analysis using 16S rRNA pyrosequencing allows us to understand the relationship between the microbial communities of adenoids and the development of OME better.
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