Evidence map›Paper›PMID 31846752›Full record

ArticleNeuroscience2020

K

P Spaiardi, E Tavazzani, M Manca, G Russo, I Prigioni, G Biella, R Giunta, S L Johnson, W Marcotti, S Masetto

Open access · hybridAbstract read
In one paragraph

Article in Neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.3field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. The potassium channel subunit KbioRxiv : the preprint server for biology · 2024
    Article
  6. Article
  7. Review
  8. Nonquantal transmission at the vestibular hair cell-calyx synapse: KProceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  9. Signal transmission in mature mammalian vestibular hair cells.Frontiers in cellular neuroscience · 2022
    Article
  10. Current Response in CaFrontiers in neuroscience · 2021
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

P SpaiardiDepartment of Brain and Behavioral Sciences, University of Pavia, Pavia 27100, Italy.
E TavazzaniDepartment of Brain and Behavioral Sciences, University of Pavia, Pavia 27100, Italy.
M MancaDepartment of Brain and Behavioral Sciences, University of Pavia, Pavia 27100, Italy.
G RussoDepartment of Brain and Behavioral Sciences, University of Pavia, Pavia 27100, Italy.
I PrigioniDepartment of Brain and Behavioral Sciences, University of Pavia, Pavia 27100, Italy.
G BiellaDepartment of Biology and Biotechnology, University of Pavia, Pavia 27100, Italy.
R GiuntaDepartment of Brain and Behavioral Sciences, University of Pavia, Pavia 27100, Italy.
S L JohnsonDepartment of Biomedical Science, University of Sheffield, Sheffield S10 2TN, UK.
W MarcottiDepartment of Biomedical Science, University of Sheffield, Sheffield S10 2TN, UK.
S MasettoDepartment of Brain and Behavioral Sciences, University of Pavia, Pavia 27100, Italy. Electronic address: smasetto@unipv.it.
University of Pavia · ITUniversity of Sheffield · GB

Funding

Wellcome Trust 102892Wellcome Trust 102892/Z/13/Z
6 · The paper itself

Abstract

Vestibular organs of Amniotes contain two types of sensory cells, named Type I and Type II hair cells. While Type II hair cells are contacted by several small bouton nerve terminals, Type I hair cells receive a giant terminal, called a calyx, which encloses their basolateral membrane almost completely. Both hair cell types release glutamate, which depolarizes the afferent terminal by binding to AMPA post-synaptic receptors. However, there is evidence that non-vesicular signal transmission also occurs at the Type I hair cell-calyx synapse, possibly involving direct depolarization of the calyx by K

Indexed as

Action PotentialsAnimalsBiophysical PhenomenaExcitatory Postsynaptic PotentialsGlutamic AcidHair Cells, VestibularIon ChannelsMembrane PotentialsMicePotassiumPotassium Channels, Voltage-GatedSynapsesGlutamic AcidIon ChannelsPotassiumPotassium Channels, Voltage-GatedcalyxK(+) channelpatch-clampsynapseType I hair cellvestibular

Identifiers

PMID31846752
PMCPMC6985899
OpenAlexW2995968769

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.