Evidence map›Paper›PMID 31846739›Full record

ArticleNanomedicine : nanotechnology, biology, and medicine2020

Photomagnetic Prussian blue nanocubes: Synthesis, characterization, and biomedical applications.

Diego S Dumani, Jason R Cook, Kelsey P Kubelick, Jeffrey J Luci, Stanislav Y Emelianov

Abstract read
In one paragraph

Article in Nanomedicine : nanotechnology, biology, and medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Review
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  12. Neurophotonics · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Diego S DumaniWallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University School of Medicine, Atlanta, GA; School of Electrical and Computer Engineering, Georgia Institute of Technology, Atlanta, GA.
Jason R CookNanoHybrids, Inc., Austin, TX; Department of Biomedical Engineering, The University of Texas at Austin, TX.
Kelsey P KubelickWallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University School of Medicine, Atlanta, GA.
Jeffrey J LuciDepartment of Biomedical Engineering, The University of Texas at Austin, TX; Department of Neuroscience and Biomedical Imaging Center, The University of Texas at Austin, Austin, TX.
Stanislav Y EmelianovWallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University School of Medicine, Atlanta, GA; School of Electrical and Computer Engineering, Georgia Institute of Technology, Atlanta, GA. Electronic address: stas@gatech.edu.

Funding

Acoustic Imaging of Sentinel Node Metastasis using Plasmonic NanosensorsR01EB008101 · NIBIB · UNIVERSITY OF TEXAS AT AUSTIN · PI EMELIANOV, STANISLAV Y, SOKOLOV, KONSTANTIN V · 2007 to 2015
$3.6M
Trimodal Vitality Imaging of Neural Progenitor Cells in the Spinal CordR01NS117613 · NINDS · GEORGIA INSTITUTE OF TECHNOLOGY · PI EMELIANOV, STANISLAV Y · 2020 to 2025
$3.0M
Functional, cellular, and molecular imaging and therapy monitoring using ultrasouR01CA158598 · NCI · UNIVERSITY OF TEXAS AT AUSTIN · PI EMELIANOV, STANISLAV Y, ESTEVA, FRANCISCO J · 2012 to 2018
$2.8M
Comprehensive Training Program in Imaging Science and InformaticsT32EB007507 · NIBIB · UNIVERSITY OF TEXAS AT AUSTIN · PI MARKEY, MIA K, RYLANDER, HENRY GRADY · 2009 to 2024
$2.7M
Magnetic Steering and Longitudinal Visualization of Stem Cells for Trabecular Meshwork Therapy in GlaucomaR01EY030071 · NEI · GEORGIA INSTITUTE OF TECHNOLOGY · PI EMELIANOV, STANISLAV Y, ETHIER, C ROSS · 2019 to 2022
$2.3M
Molecular photothermal therapy of cancer using targeted metal nanoparticlesR01CA149740 · NCI · UNIVERSITY OF TEXAS AT AUSTIN · PI EMELIANOV, STANISLAV Y · 2010 to 2014
$1.6M
Ultrasound-guided photoacoustic imaging and tracking of stem cells in the spinal cordR21NS112885 · NINDS · GEORGIA INSTITUTE OF TECHNOLOGY · PI EMELIANOV, STANISLAV Y · 2020 to 2020
$434k
NCI NIH HHS R01 CA149740NCI NIH HHS R01 CA158598NEI NIH HHS R01 EY030071NIBIB NIH HHS R01 EB008101NIBIB NIH HHS T32 EB007507NINDS NIH HHS R01 NS117613NINDS NIH HHS R21 NS112885
6 · The paper itself

Abstract

Nanoparticles play an important role in biomedicine. We have developed a method for size-controlled synthesis of photomagnetic Prussian blue nanocubes (PBNCs) using superparamagnetic iron oxide nanoparticles (SPIONs) as precursors. The developed PBNCs have magnetic and optical properties desired in many biomedical diagnostic and therapeutic applications. Specifically, the size-tunable photomagnetic PBNCs exhibit high magnetic saturation, strong optical absorption with a peak at approximately 700 nm, and superior photostability. Our studies demonstrate that PBNCs can be used as MRI and photoacoustic imaging contrast agents in vivo. We also showed the utility of PBNCs for labeling and magnetic manipulation of cells. Dual magnetic and optical properties, together with excellent biocompatibility, render PBNCs an attractive contrast agent for both diagnostic and therapeutic applications. The use SPIONs as precursors for PBNCs provides flexibility and allows researchers to design theranostic agents according to required particle size, optical, and magnetic properties.

Indexed as

AnimalsContrast MediaFemaleFerric CompoundsFerrocyanidesMagnetic Resonance ImagingMetal NanoparticlesMiceMicroscopy, Electron, TransmissionPhotoacoustic TechniquesSpectrometry, X-Ray EmissionContrast MediaFerric Compoundsferric ferrocyanideferric oxideFerrocyanidesImagingMagnetic nanoparticleNanoparticlesPhotomagneticPrussian blueSize control

Identifiers

PMID31846739
PMCPMC7160738

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.