Evidence map›Paper›PMID 31846640›Full record

Trial reportThe Annals of thoracic surgery2020

Does Tumor FDG-PET Avidity Represent Enhanced Glycolytic Metabolism in Non-Small Cell Lung Cancer?

Kemp H Kernstine, Brandon Faubert, Quyen N Do, Thomas J Rogers, Christopher T Hensley, Ling Cai, Jose Torrealba, Dwight Oliver, Jason W Wachsmann, Robert E Lenkinski and 2 more

Open access · greenAbstract readClinical Trial
In one paragraph

Trial report in The Annals of thoracic surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Correlation ofScientific reports · 2025
    Article
  4. Potential Application of the Myocardial Scintigraphy Agent [International journal of molecular sciences · 2024
    Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. Review
  12. Article
  13. If It Works, Don't Touch It? A Cell-Based Approach to Studying 2-[Pharmaceuticals (Basel, Switzerland) · 2021
    Article
  14. Review
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Kemp H KernstineDepartment of Cardiovascular and Thoracic Surgery, University of Texas Southwestern, Dallas, Texas. Electronic address: kemp.kernstine@utsouthwestern.edu.
Brandon FaubertChildren's Medical Center Research Institute, University of Texas Southwestern, Dallas, Texas.
Quyen N DoDepartment of Radiology, University of Texas Southwestern, Dallas, Texas.
Thomas J RogersChildren's Medical Center Research Institute, University of Texas Southwestern, Dallas, Texas.
Christopher T HensleyChildren's Medical Center Research Institute, University of Texas Southwestern, Dallas, Texas.
Ling CaiChildren's Medical Center Research Institute, University of Texas Southwestern, Dallas, Texas; Quantitative Biomedical Research Center, University of Texas Southwestern, Dallas, Texas.
Jose TorrealbaDepartment of Pathology, University of Texas Southwestern, Dallas, Texas.
Dwight OliverDepartment of Pathology, University of Texas Southwestern, Dallas, Texas.
Jason W WachsmannDepartment of Radiology, University of Texas Southwestern, Dallas, Texas.
Robert E LenkinskiDepartment of Radiology, University of Texas Southwestern, Dallas, Texas; Advanced Imaging Research Center, University of Texas Southwestern, Dallas, Texas.
Craig R MalloyDepartment of Radiology, University of Texas Southwestern, Dallas, Texas; Advanced Imaging Research Center, University of Texas Southwestern, Dallas, Texas; Department of Internal Medicine, University of Texas Southwestern, Dallas, Texas.
Ralph J DeberardinisChildren's Medical Center Research Institute, University of Texas Southwestern, Dallas, Texas; Department of Pediatrics, University of Texas Southwestern, Dallas, Texas; Eugene McDermott Center for Human Growth and Development, University of Texas Southwestern, Dallas, Texas; Howard Hughes Medical Institute, Chevy Chase, Maryland.
The University of Texas Southwestern Medical Center · USChildren's Medical Center · USAdvanced Imaging Research (United States) · US

Funding

TR&D 3: Imaging Carbohydrate MetabolismP41EB015908 · NIBIB · UT SOUTHWESTERN MEDICAL CENTER · PI MALLOY, CRAIG R · 2012 to 2021
$10.9M
Metabolic Regulators of Tumor Growth and ProgressionR35CA220449 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI RALPH J DEBERARDINIS · 2017 to 2026
$9.4M
NCI NIH HHS R35 CA220449NIBIB NIH HHS P41 EB015908
6 · The paper itself

Abstract

backgroundIn non-small cell lung cancer (NSCLC),

methodsIn this prospective Institutional Review Board-approved clinical trial, 52 untreated potentially resectable confirmed NSCLC patients underwent FDG-PET computed tomography. During the surgical procedure, the patients were infused with

resultsFor each patient,

conclusionsSUV

Indexed as

AdultAgedAged, 80 and overCarcinoma, Non-Small-Cell LungFemaleFluorodeoxyglucose F18GlycolysisHumansLung NeoplasmsMaleMiddle AgedPositron-Emission TomographyPredictive Value of TestsProspective StudiesRadiopharmaceuticalsTomography, X-Ray ComputedFluorodeoxyglucose F18Radiopharmaceuticals

Identifiers

PMID31846640
PMCPMC7370816
OpenAlexW2995989222

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.