Evidence map›Paper›PMID 31846621›Full record

ArticleInternational journal for parasitology2020

Characterising interactions between co-infecting parasites using age-intensity profiles.

Andrew W Park, Vanessa O Ezenwa

Abstract read
In one paragraph

Article in International journal for parasitology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Andrew W ParkOdum School of Ecology, Dept. of Infectious Diseases, College of Veterinary Medicine, and Center for the Ecology of Infectious Diseases, University of Georgia, Athens, GA 30602, United States. Electronic address: awpark@uga.edu.
Vanessa O EzenwaOdum School of Ecology, Dept. of Infectious Diseases, College of Veterinary Medicine, and Center for the Ecology of Infectious Diseases, University of Georgia, Athens, GA 30602, United States.

Funding

Coupled Macroparasite-Microparasite Interactions: Ecological and Evolutionary Consequences of CoinfectionR01GM131319 · NIGMS · YALE UNIVERSITY · PI EZENWA, VANESSA · 2018 to 2021
$1.8M
NIGMS NIH HHS R01 GM131319
6 · The paper itself

Abstract

Interactions between co-infecting parasite species can impact transmission. Whether co-infection is beneficial or detrimental to a target parasite, and whether the mechanism involves changes in host susceptibility or parasite clearance, can be difficult to assess. We demonstrate the potential for host age-parasite intensity curves to allow assessment of these factors. A model is developed to generate predictions and test these predictions using helminth parasites of white-tailed deer (Odocoileus virginianus). We identify three beneficial interactions involving five helminth species, including susceptibility and clearance-based mechanisms. Our results suggest that analysis of age-intensity data represents a new tool for assessing the nature and strength of co-infecting parasite interactions.

Indexed as

AnimalsCoinfectionDeerDisease SusceptibilityDisease Transmission, InfectiousHelminthsHost-Parasite InteractionsModels, TheoreticalClearanceCo-infectionInteractionModelPeak-shiftSusceptibility

Identifiers

PMID31846621
PMCPMC7101524

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.