Evidence map›Paper›PMID 31846581›Full record

ArticleThe journal of physical chemistry. B2020

Qingqing Chen, Shiping Xu, Xingyu Lu, Michael V Boeri, Yuliya Pepelyayeva, Elizabeth L Diaz, Sunil-Datta Soni, Marc Allaire, Martin B Forstner, Brian J Bahnson and 1 more

Open access · greenAbstract read
In one paragraph

Article in The journal of physical chemistry. B, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Exploring Sulfur Sites in Proteins via Triple-ResonanceJournal of the American Chemical Society · 2023
    Article
  4. Article
  5. Journal of biomolecular NMR · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Qingqing ChenDepartment of Chemistry and Biochemistry , University of Delaware , Newark , Delaware 19716 , United States.
Shiping XuDepartment of Chemistry and Biochemistry , University of Delaware , Newark , Delaware 19716 , United States.
Xingyu LuDepartment of Chemistry and Biochemistry , University of Delaware , Newark , Delaware 19716 , United States.
Michael V BoeriDepartment of Chemistry and Biochemistry , University of Delaware , Newark , Delaware 19716 , United States.ORCID 0000-0001-5374-2380
Yuliya PepelyayevaDepartment of Chemistry and Biochemistry , University of Delaware , Newark , Delaware 19716 , United States.
Elizabeth L DiazDepartment of Chemistry and Biochemistry , University of Delaware , Newark , Delaware 19716 , United States.
Sunil-Datta SoniNeuroscience Department, Medical Toxicology Research Division , U.S. Army Medical Research Institute of Chemical Defense , 8350 Ricketts Point Road , Gunpowder , Maryland 21010 , United States.
Marc AllaireBerkeley Center for Structural Biology, Molecular Biophysics & Integrated Bioimaging , Lawrence Berkeley National Laboratory , Berkeley , California 94720 , United States.
Martin B ForstnerDepartment of Chemistry and Biochemistry , University of Delaware , Newark , Delaware 19716 , United States.
Brian J BahnsonDepartment of Chemistry and Biochemistry , University of Delaware , Newark , Delaware 19716 , United States.
Sharon RozovskyDepartment of Chemistry and Biochemistry , University of Delaware , Newark , Delaware 19716 , United States.ORCID 0000-0003-4902-0777
University of Delaware · USUnited States Army Medical Research Institute of Infectious Diseases · USLawrence Berkeley National Laboratory · USWestlake University · CN

Funding

This renovation project will create over 1455 sq. ft. of state- of-the-art reseaP20GM104316 · NIGMS · UNIVERSITY OF DELAWARE · PI FOX, JOSEPH M · 2014 to 2024
$26.8M
Pilot Research Subproject ProgramP30GM110758 · NIGMS · UNIVERSITY OF DELAWARE · PI BEEBE, THOMAS PAUL · 2014 to 2018
$5.8M
CHEMISTRY-BIOLOGY INTERFACE PREDOCTORAL TRAININGT32GM008550 · NIGMS · UNIVERSITY OF DELAWARE · PI BAHNSON, BRIAN J · 1994 to 2018
$5.0M
Pilatus 6mS10OD021832 · OD · UNIVERSITY OF CALIFORNIA BERKELEY · PI ADAMS, PAUL DAVID · 2016 to 2016
$980k
Howard Hughes Medical InstituteNIGMS NIH HHS P20 GM104316NIGMS NIH HHS P30 GM110758NIGMS NIH HHS T32 GM008550NIH HHS S10 OD021832
6 · The paper itself

Abstract

Sulfur is critical for the correct structure and proper function of proteins. Yet, lacking a sensitive enough isotope, nuclear magnetic resonance (NMR) experiments are unable to deliver for sulfur in proteins the usual wealth of chemical, dynamic, and structural information. This limitation can be circumvented by substituting sulfur with selenium, which has similar physicochemical properties and minimal impact on protein structures but possesses an NMR compatible isotope (

Indexed as

IsotopesMolecular ConformationNuclear Magnetic Resonance, BiomolecularProteinsSeleniumSelenomethionineIsotopesProteinsSeleniumSelenium-77Selenomethionine

Identifiers

PMID31846581
PMCPMC8088340
OpenAlexW2912771594

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.