Evidence map›Paper›PMID 31846423›Full record

ArticleeLife2019

Crl activates transcription by stabilizing active conformation of the master stress transcription initiation factor.

Juncao Xu, Kaijie Cui, Liqiang Shen, Jing Shi, Lingting Li, Linlin You, Chengli Fang, Guoping Zhao, Yu Feng, Bei Yang and 1 more

Open access · goldAbstract read
In one paragraph

Article in eLife, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 33 citations in OpenAlex.

  1. Bone matrix proteins: regulators of skeletal remodeling and repair.Journal of bone and mineral metabolism · 2026
    Review
  2. Article
  3. Article
  4. RpoS and the bacterial general stress response.Microbiology and molecular biology reviews : MMBR · 2024
    Review
  5. Article
  6. A negative feedback loop is critical for recovery of RpoS after stress inbioRxiv : the preprint server for biology · 2023
    Article
  7. Computational design of N-linked glycans for high throughput epitope profiling.Protein science : a publication of the Protein Society · 2023
    Article
  8. Article
  9. An SI3-σ arch stabilizes cyanobacteria transcription initiation complex.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  10. Article
  11. Article
  12. Review
  13. Multi-omics on our multitudes.Nature genetics · 2022
    Article
  14. Article
  15. Review
  16. Review
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Juncao Xu *Key Laboratory of Synthetic Biology,CAS Center for Excellence in Molecular Plant Sciences, Shanghai Institute of Plant Physiology and Ecology, Chinese Academy of Sciences, Shanghai, China.
Kaijie Cui *University of Chinese Academy of Sciences, Beijing, China.
Liqiang ShenKey Laboratory of Synthetic Biology,CAS Center for Excellence in Molecular Plant Sciences, Shanghai Institute of Plant Physiology and Ecology, Chinese Academy of Sciences, Shanghai, China.
Jing ShiDepartment of Biophysics, Zhejiang University School of Medicine, Hangzhou, China.
Lingting LiKey Laboratory of Synthetic Biology,CAS Center for Excellence in Molecular Plant Sciences, Shanghai Institute of Plant Physiology and Ecology, Chinese Academy of Sciences, Shanghai, China.
Linlin YouKey Laboratory of Synthetic Biology,CAS Center for Excellence in Molecular Plant Sciences, Shanghai Institute of Plant Physiology and Ecology, Chinese Academy of Sciences, Shanghai, China.
Chengli FangKey Laboratory of Synthetic Biology,CAS Center for Excellence in Molecular Plant Sciences, Shanghai Institute of Plant Physiology and Ecology, Chinese Academy of Sciences, Shanghai, China.
Guoping ZhaoKey Laboratory of Synthetic Biology,CAS Center for Excellence in Molecular Plant Sciences, Shanghai Institute of Plant Physiology and Ecology, Chinese Academy of Sciences, Shanghai, China.
Yu FengDepartment of Biophysics, Zhejiang University School of Medicine, Hangzhou, China.
Bei YangShanghai Institute for Advanced Immunochemical Studies, ShanghaiTech University, Shanghai, China.ORCID 0000-0001-5389-3859
Yu ZhangKey Laboratory of Synthetic Biology,CAS Center for Excellence in Molecular Plant Sciences, Shanghai Institute of Plant Physiology and Ecology, Chinese Academy of Sciences, Shanghai, China.ORCID 0000-0002-1778-8389
Chinese Academy of Sciences · CNShanghaiTech University · CNSir Run Run Shaw Hospital · CNChinese University of Hong Kong · HK

Funding

Chinese Academy of Sciences QYZDB-SSW-SMC005Chinese Academy of Sciences XDB29020000Ministry of Science and Technology of the People's Republic of China 2018YFA0900701National Natural Science Foundation of China 31822001National Natural Science Foundation of China 31870047
6 · The paper itself

Abstract

σ

Indexed as

Transcription, GeneticAmino Acid SequenceCryoelectron MicroscopyDNA-Directed RNA PolymerasesEscherichia coliEscherichia coli ProteinsModels, MolecularProtein BindingProtein ConformationProtein StabilitySigma FactorTranscription Factorscrl protein, E coliDNA-Directed RNA PolymerasesEscherichia coli ProteinsSigma FactorTranscription FactorschromosomesCrlE. coligene expressionRNA polymerasesigma factorstress responsetranscription activationtranscription factors

Identifiers

PMID31846423
PMCPMC6917491
OpenAlexW2994666385

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.