Evidence map›Paper›PMID 31846122›Full record

ArticleMagnetic resonance in medicine2020

Controlled saturation magnetization transfer for reproducible multivendor variable flip angle T

Rui Pedro A G Teixeira, Radhouene Neji, Tobias C Wood, Ana A Baburamani, Shaihan J Malik, Joseph V Hajnal

Abstract read
In one paragraph

Article in Magnetic resonance in medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Mapping a reproducible water fraction and TMagnetic resonance in medicine · 2026
    Article
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  4. Article
  5. Normative trajectories of RImaging neuroscience (Cambridge, Mass.) · 2025
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  7. Quantitative TImaging neuroscience (Cambridge, Mass.) · 2025
    Article
  8. Article
  9. Article
  10. BMagnetic resonance in medicine · 2023
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Toward nonparametric diffusion-Magnetic resonance in medicine · 2021
    Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rui Pedro A G TeixeiraCenter for the Developing Brain, School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom.ORCID 0000-0001-6508-9315
Radhouene NejiBiomedical Engineering Department, School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom.
Tobias C WoodDepartment of Neuroimaging, King's College London, London, United Kingdom.ORCID 0000-0001-7640-5520
Ana A BaburamaniCenter for the Developing Brain, School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom.
Shaihan J MalikCenter for the Developing Brain, School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom.ORCID 0000-0001-8925-9032
Joseph V HajnalCenter for the Developing Brain, School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom.

Funding

Department of HealthWellcome TrustWellcome Trust WT 203148/Z/16/Z
6 · The paper itself

Abstract

purposeThe widespread clinical application of quantitative MRI has been hindered by a lack of reproducibility across sites and vendors. Previous work has attributed this to incorrect B

methodsThree healthy volunteers were scanned on scanners from 3 vendors (GE Healthcare, Philips, Siemens). An extensive set of images necessary for joint T

resultsHarmonized RF spoiling conditions are insufficient to ensure good cross-vendor reproducibility. Controlled saturation magnetization transfer allows cross-protocol variability to be reduced from 18.3% to 4.0%. Whole-brain variability using the same protocol was reduced from a maximum of 19% to 4.5% across sites. Both CSMT and native vendor RF conditions have a reported variability of less than 5% for repeat measures on the same vendor.

conclusionMagnetization transfer effects are a major contributor to intersite/intrasite variability of T

Indexed as

AlgorithmsMagnetic Resonance ImagingBrainHealthy VolunteersHumansReproducibility of ResultsCSMTDESPOTJSRmagnetization transferrelaxometryreproducibilityT1 mappingT2 mapping

Identifiers

PMID31846122
PMCPMC7154666

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.