Evidence map›Paper›PMID 31846121›Full record

ArticleMagnetic resonance in medicine2020

First in-vivo human imaging at 10.5T: Imaging the body at 447 MHz.

Xiaoxuan He, M Arcan Ertürk, Andrea Grant, Xiaoping Wu, Russell L Lagore, Lance DelaBarre, Yiğitcan Eryaman, Gregor Adriany, Eddie J Auerbach, Pierre-François Van de Moortele and 2 more

Abstract read
In one paragraph

Article in Magnetic resonance in medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. First In VivoMagnetic resonance in medicine · 2026
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Acoustic noise reduction in the NexGen 7 T scanner.Magnetic resonance in medicine · 2024
    Article
  20. A Quantitative Comparison ofSensors (Basel, Switzerland) · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Xiaoxuan HeCenter for Magnetic Resonance Research, University of Minnesota, Minneapolis, Minnesota.ORCID 0000-0003-0885-912X
M Arcan ErtürkCenter for Magnetic Resonance Research, University of Minnesota, Minneapolis, Minnesota.
Andrea GrantCenter for Magnetic Resonance Research, University of Minnesota, Minneapolis, Minnesota.
Xiaoping WuCenter for Magnetic Resonance Research, University of Minnesota, Minneapolis, Minnesota.ORCID 0000-0001-6021-9088
Russell L LagoreCenter for Magnetic Resonance Research, University of Minnesota, Minneapolis, Minnesota.
Lance DelaBarreCenter for Magnetic Resonance Research, University of Minnesota, Minneapolis, Minnesota.
Yiğitcan EryamanCenter for Magnetic Resonance Research, University of Minnesota, Minneapolis, Minnesota.
Gregor AdrianyCenter for Magnetic Resonance Research, University of Minnesota, Minneapolis, Minnesota.
Eddie J AuerbachCenter for Magnetic Resonance Research, University of Minnesota, Minneapolis, Minnesota.
Pierre-François Van de MoorteleCenter for Magnetic Resonance Research, University of Minnesota, Minneapolis, Minnesota.ORCID 0000-0002-6941-5947
Kâmil UğurbilCenter for Magnetic Resonance Research, University of Minnesota, Minneapolis, Minnesota.
Gregory J MetzgerCenter for Magnetic Resonance Research, University of Minnesota, Minneapolis, Minnesota.

Funding

TRD4 - Ultrahigh Field Engineering and SafetyP41EB027061 · NIBIB · UNIVERSITY OF MINNESOTA · PI Gregory John Metzger, KAMIL UGURBIL · 2019 to 2026
$11.7M
NMR Imaging and SpectroscopyP41EB015894 · NIBIB · UNIVERSITY OF MINNESOTA · PI UGURBIL, KAMIL · 2012 to 2017
$8.4M
CONSOLE FOR 10.5 TESLA WHOLE BODY MRI SYSTEMS10RR029672 · NCRR · UNIVERSITY OF MINNESOTA · PI UGURBIL, KAMIL · 2010 to 2010
$7.8M
Development of an Optimal MRI Platform for Prostate Investigations at 7 TeslaR01CA155268 · NCI · UNIVERSITY OF MINNESOTA · PI METZGER, GREGORY JOHN · 2012 to 2016
$2.0M
NCI NIH HHS R01 CA155268NCRR NIH HHS S10 RR029672NIBIB NIH HHS P41 EB015894NIBIB NIH HHS P41 EB027061
6 · The paper itself

Abstract

purposeTo investigate the feasibility of imaging the human torso and to evaluate the performance of several radiofrequency (RF) management strategies at 10.5T.

methodsHealthy volunteers were imaged on a 10.5T whole-body scanner in multiple target anatomies, including the prostate, hip, kidney, liver, and heart. Phase-only shimming and spoke pulses were used to demonstrate their performance in managing the

resultsHigh-quality images were acquired and demonstrated excellent overall contrast and signal-to-noise ratio. The experimental results matched well with predictions and suggested good translational capabilities of the RF management strategies previously developed at 7T. Phase-only shimming provided increased efficiency, but showed pronounced limitations in homogeneity, demonstrating the need for the increased degrees of freedom made possible through single- and multispoke RF pulse design.

conclusionThe first in-vivo human imaging was successfully performed at 10.5T using previously developed RF management strategies. Further improvement in RF coils, transmit chain, and full integration of parallel transmit functionality are needed to fully realize the benefits of 10.5T.

Indexed as

Image Interpretation, Computer-AssistedMagnetic Resonance ImagingHeartHumansMaleRadio WavesSignal-To-Noise Ratio10.5Tbody imagingmagnetic resonance imagingparallel transmitultra-high field imaging

Identifiers

PMID31846121
PMCPMC7083701

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.