Evidence map›Paper›PMID 31846019›Full record

SynthesisJAMA2019

Does This Patient Have Hip Osteoarthritis?: The Rational Clinical Examination Systematic Review.

David Metcalfe, Daniel C Perry, Henry A Claireaux, David L Simel, Cheryl K Zogg, Matthew L Costa

Open access · greenAbstract readSystematic Review
In one paragraph

Synthesis in JAMA, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 60 citations in OpenAlex.

  1. Antithrombotic prophylaxis following total hip arthroplasty: a level I Bayesian network meta-analysis.Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology · 2024
    Pooled it
  2. Article
  3. Article
  4. Review
  5. Review
  6. Review
  7. Osteoarthritis.Nature reviews. Disease primers · 2025
    Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Epidemiology of Hip Osteoarthritis: The Johnston County Osteoarthritis Project.HSS journal : the musculoskeletal journal of Hospital for Special Surgery · 2023
    Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

David MetcalfeNuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom.
Daniel C PerryNuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom.
Henry A ClaireauxNuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom.
David L SimelDurham Veterans Affairs Health System, Durham, North Carolina.
Cheryl K ZoggYale School of Medicine, Yale University, New Haven, Connecticut.
Matthew L CostaNuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom.
University of Oxford · GBDuke University · USNuffield Orthopaedic Centre · GBYale University · US

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM007205 · NIGMS · YALE UNIVERSITY · PI KAZMIERCZAK, BARBARA I · 1985 to 2019
$42.9M
The ED.TRAUMA Study: Evaluating the Discordance ofTrauma Readmission And Unanticipated Mortality in the Assessment of hospital qualityF30AG066371 · NIA · YALE UNIVERSITY · PI ZOGG, CHERYL K · 2019 to 2022
$163k
Department of Health CS-2014-14-012NIA NIH HHS F30 AG066371NIGMS NIH HHS T32 GM007205
6 · The paper itself

Abstract

importanceHip osteoarthritis (OA) is a common cause of pain and disability.

objectiveTo identify the clinical findings that are most strongly associated with hip OA. DATA SOURCES: Systematic search of MEDLINE, PubMed, EMBASE, and CINAHL from inception until November 2019. STUDY SELECTION: Included studies (1) quantified the accuracy of clinical findings (history, physical examination, or simple tests) and (2) used plain radiographs as the reference standard for diagnosing hip OA. DATA EXTRACTION AND SYNTHESIS: Studies were assigned levels of evidence using the Rational Clinical Examination scale and assessed for risk of bias using the Quality Assessment of Diagnostic Accuracy Studies tool. Data were extracted using individual hips as the unit of analysis and only pooled when findings were reported in 3 or more studies. MAIN OUTCOMES AND MEASURES: Sensitivity, specificity, and likelihood ratios (LRs).

resultsSix studies were included, with data from 1110 patients and 1324 hips, of which 509 (38%) showed radiographic evidence of OA. Among patients presenting to primary care physicians with hip or groin pain, the affected hip showed radiographic evidence of OA in 34% of cases. A family history of OA, personal history of knee OA, or pain on climbing stairs or walking up slopes all had LRs of 2.1 (sensitivity range, 33%-68%; specificity range, 68%-84%; broadest LR range: 95% CI, 1.1-3.8). To identify patients most likely to have OA, the most useful findings were squat causing posterior pain (sensitivity, 24%; specificity, 96%; LR, 6.1 [95% CI, 1.3-29]), groin pain on passive abduction or adduction (sensitivity, 33%; specificity, 94%; LR, 5.7 [95% CI, 1.6-20]), abductor weakness (sensitivity, 44%; specificity, 90%; LR, 4.5 [95% CI, 2.4-8.4]), and decreased passive hip adduction (sensitivity, 80%; specificity, 81%; LR, 4.2 [95% CI, 3.0-6.0]) or internal rotation (sensitivity, 66%; specificity, 79%; LR, 3.2 [95% CI, 1.7-6.0]) as measured by a goniometer or compared with the contralateral leg. The presence of normal passive hip adduction was most useful for suggesting the absence of OA (negative LR, 0.25 [95% CI, 0.11-0.54]). CONCLUSIONS AND RELEVANCE: Simple tests of hip motion and observing for pain during that motion were helpful in distinguishing patients most likely to have OA on plain radiography from those who will not. A combination of findings efficiently detects those most likely to have severe hip OA.

Indexed as

Physical ExaminationRadiographyDiagnosis, DifferentialFemaleHip JointHumansMaleMiddle AgedOsteoarthritis, HipPainRange of Motion, ArticularSensitivity and Specificity

Identifiers

PMID31846019
PMCPMC7583647
OpenAlexW2995142386

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.