Evidence map›Paper›PMID 31845918›Full record

ArticleOncology nursing forum2020

Symptom Clusters in Breast Cancer Survivors: A Latent Class Profile Analysis.

Lena Lee, Alyson Ross, Kathleen Griffith, Roxanne E Jensen, Gwenyth R Wallen

Abstract read
In one paragraph

Article in Oncology nursing forum, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Associations of frailty with symptoms, and HRQOL in older cancer survivors after cancer treatments: a systematic review and meta-analyses.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024
    Pooled it
  2. Mapping Systematic Reviews of Breast Cancer Survivorship Interventions: A Network Analysis.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2022
    Pooled it
  3. Profiles of quality of life among US young adult cancer survivors and their associations with potential psychosocial intervention targets of hope and psychological flexibility.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025
    Trial
  4. Latent profile analysis for assessing symptom clusters in women with breast cancer.Journal of cancer survivorship : research and practice · 2026
    Article
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  14. Acupuncture for the treatment of the pain-fatigue-sleep disturbance-numbness/tingling symptom cluster in breast cancer survivors: a feasibility trial.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Article
  15. Article
  16. Comparing symptom clusters in cancer survivors by cancer diagnosis: A latent class profile analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Article
  17. Article
  18. Treating persistent pain after breast cancer: practice gaps and future directions.Journal of cancer survivorship : research and practice · 2023
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lena LeeNational Institutes of Health Clinical Center.
Alyson RossNational Institutes of Health Clinical Center.
Kathleen GriffithGeorge Washington University.
Roxanne E JensenNational Cancer Institute.
Gwenyth R WallenNational Institutes of Health Clinical Center.

Funding

Intramural NIH HHS Z99 CL999999
6 · The paper itself

Abstract

objectivesTo identify symptom clusters in breast cancer survivors and to determine sociodemographic and clinical characteristics influencing symptom cluster membership. SAMPLE AND

settingThe authors performed a cross-sectional secondary analysis of data obtained from a community-based cancer registry-linked survey with 1,500 breast cancer survivors 6-13 months following a breast cancer diagnosis. METHODS AND VARIABLES: Symptom clusters were identified using latent class profile analysis of four patient-reported symptoms (pain, fatigue, sleep disturbance, and depression) with custom PROMIS® short forms.

resultsFour distinct classes were identified. IMPLICATIONS FOR NURSING: Common symptom clusters may lead to better prevention and treatment strategies that target a group of symptoms. Results also suggest that certain factors place patients at high risk for symptom burden, which can guide tailored interventions.

Indexed as

AdultAgedAged, 80 and overBreast NeoplasmsCancer SurvivorsCross-Sectional StudiesFemaleHumansMiddle AgedSocioeconomic FactorsSymptom AssessmentSyndromeYoung Adultbreast cancersurvivorssymptom burdensymptom clusters

Identifiers

PMID31845918
PMCPMC7313389

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.