Evidence map›Paper›PMID 31845917›Full record

ArticleOncology nursing forum2020

Mental Illness and BRCA1/2 Genetic Testing Intention Among Multiethnic Women Undergoing Screening Mammography.

Tarsha Jones, Katherine Freeman, Marra Ackerman, Meghna S Trivedi, Thomas Silverman, Peter Shapiro, Rita Kukafka, Katherine D Crew

Abstract read
In one paragraph

Article in Oncology nursing forum, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Anxiety and depression among racial/ethnic minorities and impoverished women testing positive for BRCA1/2 mutations in the United States.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Tarsha JonesFlorida Atlantic University.
Katherine FreemanFlorida Atlantic University.
Marra AckermanNew York University Langone Medical Center.
Meghna S TrivediHerbert Irving Comprehensive Cancer Center.
Thomas SilvermanColumbia University.
Peter ShapiroColumbia University.
Rita KukafkaColumbia University.
Katherine D CrewColumbia University.

Funding

Tumor Biology and Microenvironment ProgramP30CA013696 · NCI · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI Anil K Rustgi · 1985 to 2026
$115.3M
Clinical and Translational Science AwardUL1TR000040 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GINSBERG, HENRY N · 2012 to 2015
$26.2M
OMOP information model for eMERGE phenotypingU01HG008680 · NHGRI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Wendy K Chung, GEORGE M HRIPCSAK · 2015 to 2026
$13.3M
Increasing breast cancer chemoprevention in the primary care settingR01CA177995 · NCI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI CREW, KATHERINE D, KUKAFKA, RITA · 2014 to 2018
$3.5M
Multicenter trial of decision support for breast cancer chemopreventionR01CA226060 · NCI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI CREW, KATHERINE D, KUKAFKA, RITA · 2019 to 2023
$3.3M
NCATS NIH HHS UL1 TR000040NCI NIH HHS P30 CA013696NCI NIH HHS R01 CA177995NCI NIH HHS R01 CA226060NHGRI NIH HHS U01 HG008680
6 · The paper itself

Abstract

objectivesTo examine associations between patient-reported mental illness diagnosis and symptoms and BRCA1/2 genetic testing intention among women undergoing screening mammography. SAMPLE &

setting100 multiethnic women of lower socioeconomic status who were undergoing mammography screening and met family history criteria for BRCA1/2 genetic testing. METHODS & VARIABLES: Descriptive and bivariate nonparametric statistics and multivariate logistic regression were used to examine associations between mental illness and genetic testing intention. Variables were anxiety, depression, patient-reported mental illness diagnosis and symptoms, and testing intention.

resultsPrevalence rates of mental illness symptoms were 36% for clinically significant depression and 36% for anxiety. Although 76% of participants intended to undergo genetic testing, only 5% had completed testing. History of mental illness and elevated levels of anxiety and depressive symptoms were positively correlated with testing intention in the bivariate analysis. In multivariate analysis, only younger age and less education were associated with testing intention. IMPLICATIONS FOR NURSING: Future studies should address psychosocial needs and other competing barriers at the patient, provider, and healthcare system levels to increase access to BRCA1/2 genetic testing among multiethnic women.

Indexed as

AdultAgedAttitude to HealthBRCA1 ProteinBreast NeoplasmsEarly Detection of CancerFemaleHumansLogistic ModelsMammographyMass ScreeningMental DisordersMiddle AgedNew York CityBRCA1 ProteinBRCA1 protein, humanBRCA1/2genetic testingmammographymental illnessmultiethnic women

Identifiers

PMID31845917
PMCPMC7295180

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.