Evidence map›Paper›PMID 31845598›Full record

ArticleIntegrative cancer therapies

Lemongrass Extract Possesses Potent Anticancer Activity Against Human Colon Cancers, Inhibits Tumorigenesis, Enhances Efficacy of FOLFOX, and Reduces Its Adverse Effects.

Ivan Ruvinov, Christopher Nguyen, Benjamin Scaria, Caleb Vegh, Ola Zaitoon, Kiruthika Baskaran, Ali Mehaidli, Malika Nunes, Siyaram Pandey

Open access · goldAbstract read
In one paragraph

Article in Integrative cancer therapies. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 41 citations in OpenAlex.

  1. Article
  2. Frontiers in immunology · 2025
    Article
  3. Phytochemical Profile ofFoods (Basel, Switzerland) · 2024
    Article
  4. Review
  5. Review
  6. Molecules (Basel, Switzerland) · 2023
    Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Ivan RuvinovUniversity of Windsor, Windsor, Ontario, Canada.
Christopher NguyenUniversity of Windsor, Windsor, Ontario, Canada.
Benjamin ScariaUniversity of Windsor, Windsor, Ontario, Canada.
Caleb VeghUniversity of Windsor, Windsor, Ontario, Canada.
Ola ZaitoonUniversity of Windsor, Windsor, Ontario, Canada.
Kiruthika BaskaranUniversity of Windsor, Windsor, Ontario, Canada.
Ali MehaidliUniversity of Windsor, Windsor, Ontario, Canada.
Malika NunesUniversity of Windsor, Windsor, Ontario, Canada.
Siyaram PandeyUniversity of Windsor, Windsor, Ontario, Canada.ORCID 0000-0002-7273-7154
University of Windsor · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Current chemotherapeutics for metastatic colorectal cancers have limited success and are extremely toxic due to nonselective targeting. Some natural extracts have been traditionally taken and have shown anticancer activity. These extracts have multiple phytochemicals that can target different pathways selectively in cancer cells. We have shown previously that lemongrass (

Indexed as

AnimalsAntineoplastic AgentsAntineoplastic Combined Chemotherapy ProtocolsApoptosisCarcinogenesisCell LineCell Transformation, NeoplasticColonic NeoplasmsCymbopogonEthanolFluorouracilHCT116 CellsHT29 CellsHumansLeucovorinMiceAntineoplastic AgentsEthanolFluorouracilLeucovorinOrganoplatinum CompoundsPlant Extractscancer preventioncolorectal cancerFOLFOXlemongrass extractnatural health productsNHP drug interactionTaxol

Identifiers

PMID31845598
PMCPMC6918039
OpenAlexW2995847504

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.