Evidence map›Paper›PMID 31845401›Full record

ArticleMagnetic resonance in medicine2020

Cerebrovascular MRI in the mouse without an exogenous contrast agent.

Jérémie P Fouquet, Réjean Lebel, Lindsay S Cahill, John G Sled, Luc Tremblay, Martin Lepage

Open access · hybridAbstract read
In one paragraph

Article in Magnetic resonance in medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

  1. Preclinical in-vivo cerebrovascular imaging in rodent models: Methods and applications in Alzheimer's disease.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2026
    Review
  2. Article
  3. Review
  4. Mouse Cardiovascular Imaging.Current protocols · 2024
    Review
  5. Review
  6. Non-invasiveCell reports methods · 2022
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Jérémie P FouquetDepartment of Nuclear Medicine and Radiobiology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, QC, Canada.ORCID 0000-0001-6815-7037
Réjean LebelDepartment of Nuclear Medicine and Radiobiology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, QC, Canada.
Lindsay S CahillMouse Imaging Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.
John G SledMouse Imaging Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.
Luc TremblayDepartment of Nuclear Medicine and Radiobiology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, QC, Canada.
Martin LepageDepartment of Nuclear Medicine and Radiobiology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, QC, Canada.
Université de Sherbrooke · CAHospital for Sick Children · CAUniversity of Toronto · CA

Funding

CIHR 273995
6 · The paper itself

Abstract

purposeTo assess the effect of a variety of anesthetic regimes on

methodsTwenty mice were imaged with a 3D

resultsThe commonly used isoflurane anesthetic leads to poor vessel conspicuity for fraction of inspired oxygen higher or equal to 21%. Dexmedetomidine and ketamine-xylazine enable the visualization of a significantly larger portion of the vasculature for the same breathing gas. Under isoflurane anesthesia, the fraction of inspired oxygen must be lowered to between 10% and 14% to obtain similar vessel conspicuity. Initial results on automatic segmentation of veins and arteries using the iron oxide positive control are also reported.

conclusion

Indexed as

AnestheticsIsofluraneAnimalsContrast MediaMagnetic Resonance ImagingMiceXylazineAnestheticsContrast MediaIsofluraneXylazineanesthesiacerebral angiographymouse brain

Identifiers

PMID31845401
PMCPMC7154782
OpenAlexW2996689579

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.