ArticlePlant molecular biology2020
Metabolome and transcriptome profiling reveals quality variation and underlying regulation of three ecotypes for Cistanche deserticola.
Article in Plant molecular biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 42 citations in OpenAlex.
- A chromosome-level genome assembly of Cistanche deserticola provides insights into its evolution and molecular mechanisms of parasitism.Plant communications · 2026Article
- Metabolome and transcriptome analyses reveal metabolic differences and identify candidate regulatory factors among three habitat types ofFrontiers in plant science · 2026Article
- Holistic concept guided quality control of traditional Chinese medicines for optimizing bioavailability.Chinese medicine · 2025Review
- Multidimensional evaluation of quality differences forFrontiers in plant science · 2025Article
- Transcriptomics and metabolomics revealed the molecular basis of the color formation in the roots ofHeliyon · 2024Article
- An omics-based characterization of Wolfiporia cocos reveals three CYP450 members involved in the biosynthetic pathway of pachymic acid.Communications biology · 2024Article
- A Review of Transcriptomics and Metabolomics in Plant Quality and Environmental Response: From Bibliometric Analysis to Science Mapping and Future Trends.Metabolites · 2024Review
- Revealing ecotype influences onFrontiers in microbiology · 2023Article
- Authenticating the geographic origins ofFrontiers in plant science · 2023Article
- Quality variation and biosynthesis of anti-inflammatory compounds forFrontiers in plant science · 2023Article
- Characteristic Volatile Organic Compound Analysis of Different Cistanches Based on HS-GC-IMS.Molecules (Basel, Switzerland) · 2022Article
- De novo full length transcriptome analysis and gene expression profiling to identify genes involved in phenylethanol glycosides biosynthesis in Cistanche tubulosa.BMC genomics · 2022Article
- Identification of Medicinal Compounds of Fagopyri Dibotryis Rhizome from Different Origins and Its Varieties Using UPLC-MS/MS-Based Metabolomics.Metabolites · 2022Article
- Structural mutations of small single copy (SSC) region in the plastid genomes of five Cistanche species and inter-species identification.BMC plant biology · 2022Article
- Genome-wide identification of bHLH transcription factors: Discovery of a candidate regulator related to flavonoid biosynthesis inFrontiers in plant science · 2022Article
- Metabolomics analysis unveils important changes involved in the salt tolerance ofFrontiers in plant science · 2022Article
- Comparison of metabolome characteristics and screening of chemical markers inPhysiology and molecular biology of plants : an international journal of functional plant biology · 2022Article
- Organ-specific, integrated omics data-based study on the metabolic pathways of the medicinal plant Bletilla striata (Orchidaceae).BMC plant biology · 2021Article
- Metabolome profiling and molecular docking analysis revealed the metabolic differences and potential pharmacological mechanisms of the inflorescence and succulent stem ofRSC advances · 2021Article
- Consequences of LED Lights on Root Morphological Traits and Compounds Accumulation inInternational journal of molecular sciences · 2021Article
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
Cistanche deserticola is a plant used both as food and medicine. We are interested in understanding how C. deserticola responds to environmental conditions. Samples were collected from three ecotypes grown in saline-alkali land, grassland and sandy land. Transcriptome and metabolome analysis were performed by using RNA-seq and LC-ESI-MS/MS. Among 578 metabolites identified, 218, 209 and 215 compounds were found differentially produced among the three ecotypes. Particularly, 2'-acetylacteoside, belonging to phenylethanoid glycosides (PhGs) is the most significantly differentially produced with a VIP > 0.5 and fold change > 2, representing a potential chemical marker to distinguish the three ecotypes. RNA-Seq analysis revealed 52,043 unigenes, and 947, 632 and 97 of them were found differentially expressed among the three ecotypes. Analysis of the correlation between the metabolome profiles and transcriptome profiles among three ecotypes identified that the 12 key genes related to PhGs biosynthesis were differentially expressed. Particularly, the expression of PAL, ALDH and GOT genes were significantly up-regulated in saline-alkali land compared to the other two. In summary, we found PhGs content was higher in saline-alkali land compared with other ecotypes. This is likely due to the up-regulation of the PhGs biosynthetic genes in response to the saline-alkali conditions.
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