Evidence map›Paper›PMID 31845302›Full record

ArticleMagma (New York, N.Y.)2020

Quantification of testicular fat deposition in the evaluation of middle-aged overweight male infertility.

Qing-Ling Li, Fei Yang, Wen-Ying Zhou, Na Cheng, Wen-Jie Tang, Yu Guo, Ruo-Mi Guo

Abstract read
PubMed Publisher
In one paragraph

Article in Magma (New York, N.Y.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Proton density fat fraction: magnetic resonance imaging applications beyond the liver.Diagnostic and interventional radiology (Ankara, Turkey) · 2022
    Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Qing-Ling LiDepartment of Radiology, The Third Affiliated Hospital, Sun Yat-Sen University, 600 Tianhe Road, Guangzhou, 510630, China.
Fei YangDepartment of Radiology, The Third Affiliated Hospital, Sun Yat-Sen University, 600 Tianhe Road, Guangzhou, 510630, China.
Wen-Ying ZhouDepartment of Laboratory, The Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China.
Na ChengDepartment of Pathology, The Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China.
Wen-Jie TangDepartment of Radiology, The Third Affiliated Hospital, Sun Yat-Sen University, 600 Tianhe Road, Guangzhou, 510630, China.
Yu GuoDepartment of Radiology, The Third Affiliated Hospital, Sun Yat-Sen University, 600 Tianhe Road, Guangzhou, 510630, China. guoyu35@mail.sysu.edu.cn.
Ruo-Mi GuoDepartment of Radiology, The Third Affiliated Hospital, Sun Yat-Sen University, 600 Tianhe Road, Guangzhou, 510630, China. guoruomi86@mail.sysu.edu.cn.ORCID http://orcid.org/0000-0002-8207-8746
Sun Yat-sen University · CN

Funding

Guangdong Medical Research Foundation A2018106National Natural Science Foundation of China 81801757Natural Science Foundation of Guangdong Province 2018A030310322Natural Science Foundation of Guangdong Province 2019A1515012051
6 · The paper itself

Abstract

objectivesTo measure the testicular volume and testicular fat deposition of middle-aged overweight men and to assess the utility of testicular fat deposition and testicular volume in determining and monitoring testicular infertility. MATERIALS AND

methodsPelvic MRI with thin slice T2WI, T1WI and mDIXON Quant was performed on 30 middle-aged overweight patients in the treatment group and 30 middle-aged overweight men in the control group. Testicular volume and testicular fat deposition were measured separately based on thin slice T2WI and the fat fraction (FF) map of mDIXON Quant, and the testicular fat deposition observed with T1WI was used as a reference for qualitative diagnosis. Testicular volume and testicular fat deposition in middle-aged overweight individuals were compared using a t test with Bonferroni correction and receiver operating characteristic (ROC) curve.

resultsThe testicular volumes (10.6-17.9 cm

conclusionThe findings suggest that the proton density fat fraction (mDIXON Quant sequence in this study) approach is a novel tool for the quantitative and objective evaluation of testicular fat deposition. Testicular fat deposition measurement is more specific than testicular volume measurement in the diagnosis of male infertility, and the mDIXON Quant is more sensitive than T1WI in the diagnosis of testicular fat deposition. Furthermore, our findings may facilitate a more accurate diagnosis and monitoring of testicular infertility, therapeutic effect, and prognosis by measuring testicular fat deposition.

Indexed as

Adipose TissueAdultArea Under CurveHumansImage Processing, Computer-AssistedInfertility, MaleMagnetic Resonance ImagingMaleMiddle AgedOverweightPelvisRetrospective StudiesROC CurveSensitivity and SpecificitySperm CountSperm MotilityAzoospermiaFat depositionFat fractionMagnetic resonance imagingTestisVolume

Identifiers

PMID31845302
OpenAlexW2996350700

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.