Evidence map›Paper›PMID 31845301›Full record

ArticleMagma (New York, N.Y.)2020

DTI of the kidney in children: comparison between normal kidneys and those with ureteropelvic junction (UPJ) obstruction.

Hansel J Otero, Juan S Calle-Toro, Carolina L Maya, Kassa Darge, Suraj D Serai

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Magma (New York, N.Y.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

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0cells of the map it votes in
5citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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5 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Hansel J OteroDepartment of Radiology, The Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine, 3401 Civic Center Blvd., Philadelphia, PA, 19104, USA.
Juan S Calle-ToroDepartment of Radiology, The Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine, 3401 Civic Center Blvd., Philadelphia, PA, 19104, USA.
Carolina L MayaDepartment of Radiology, The Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine, 3401 Civic Center Blvd., Philadelphia, PA, 19104, USA.
Kassa DargeDepartment of Radiology, The Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine, 3401 Civic Center Blvd., Philadelphia, PA, 19104, USA.
Suraj D SeraiDepartment of Radiology, The Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine, 3401 Civic Center Blvd., Philadelphia, PA, 19104, USA. serais@email.chop.edu.ORCID http://orcid.org/0000-0002-8821-0971

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo compare renal diffusion tensor imaging (DTI) parameters in patients with or without ureteropelvic junction (UPJ) obstruction.

methodsPatients that underwent functional MR urography (MRU) with renal DTI were retrospectively selected. Kidneys deemed normal on T2-weighted images and functional parameters were used as controls and compared to those kidneys with morphologic and functional findings of UPJ obstruction. DTI included a 20-direction DTI with b values of b = 0 s/mm

results118 normal kidneys from 102 patients (median age 7 years, IQR 6-15 years; 58 males and 44 females) were compared to 22 kidneys from 16 patients (median age 13 years, IQR 3-15 years; 9 males and 7 females) with UPJ obstruction. Mean FA values were significantly lower (0.31 ± 0.07; n = 22) in kidneys with UPJ obstruction than normal kidneys (0.40 ± 0.08; n = 118) (p < 0.001). ADC was marginally significantly increased (p = 0.01) and track length was not significantly different (p = 0.24).

conclusionOur results suggest that DTI-derived metrics including FA and ADC are potential biomarkers to differentiate kidneys with UPJ obstruction and assess renal parenchymal damage.

Indexed as

Diffusion Tensor ImagingAdolescentAlgorithmsChildChild, PreschoolDiagnosis, Computer-AssistedFemaleHumansImage Processing, Computer-AssistedKidneyMagnetic Resonance ImagingMaleRetrospective StudiesUreterUreteral ObstructionDiffusion tensor imagingMagnetic resonance imagingRenal DTIUPJUreteropelvic junction obstruction

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.