ArticleEnvironmental science and pollution research international2020
Mechanisms of the direct effects of oil-related contaminants on ovarian cells.
Article in Environmental science and pollution research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed, 23 citations in OpenAlex.
- The Toxic Effect of Toluene on Ovarian Cells Can Be Prevented by the MicroRNA miR-152.Physiological research · 2024Article
- Three medicinal plants affecting human ovarian cell viability, hormone release, and response to environmental contaminant toluene.Physiological research · 2023Article
- Dietary Supplementation of Flaxseed (Life (Basel, Switzerland) · 2022Article
- Toxicological Effects of Technical Xylene Mixtures on the Female Reproductive System: A Systematic Review.Toxics · 2022Review
- Toluene Can Disrupt Rat Ovarian Follicullogenesis and Steroidogenesis and Induce Both Autophagy and Apoptosis.Biology · 2021Article
- Kefir milk alleviates benzene-induced immunotoxicity and hematotoxicity in rats.Environmental science and pollution research international · 2021Article
- Buckwheat, rooibos, and vitex extracts can mitigate adverse effects of xylene on ovarian cells in vitro.Environmental science and pollution research international · 2021Article
- Effects of benzene on gilts ovarian cell functions alone and in combination with buckwheat, rooibos, and vitex.Environmental science and pollution research international · 2021Article
- Plant isoflavones can prevent adverse effects of benzene on porcine ovarian activity: an in vitro study.Environmental science and pollution research international · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 5 institutions in 4 countries.
Funding
Abstract
We studied the influence of oil-related environmental contaminants (OREC) on the viability, hormone secretion, and protein expression using cultured porcine ovarian granulosa cells. Addition of benzene and xylene promoted proliferation and apoptosis and reduced ovarian cell viability whereas toluene induced apoptosis only. The release of progesterone (P4) and oxytocin (OT) was promoted by benzene and xylene, and suppressed by toluene while prostaglandin F (PGF) output was stimulated by benzene and toluene, but not xylene. The addition of FSH to the culture medium increased ovarian cell proliferation and hormone release, but did not affect apoptosis. However, this FSH's proliferative effect has been prevented in presence of benzene. On the other hand and in the presence of FSH, toluene prevented P4 release and decreased PGF release, while xylene prevented PGF release. We concluded that OREC can affect reproductive processes by directly influencing ovarian cell proliferation, apoptosis, viability, hormone release, and response to gonadotropins.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.