Evidence map›Paper›PMID 31845227›Full record

ArticleCurrent medical science2019

Knockout of MicroRNA-155 Ameliorates the Th17/Th9 Immune Response and Promotes Wound Healing.

Chen-Rong Wang, Hong-Fei Zhu, Yong Zhu

Abstract read
PubMed Publisher
In one paragraph

Article in Current medical science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Beyond the Code: Noncoding RNAs in Skin Wound Healing.Cold Spring Harbor perspectives in biology · 2022
    Article
  9. Review
  10. Review
  11. Article
  12. miR-155: An Important Role in Inflammation Response.Journal of immunology research · 2022
    Review
  13. Review
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Chen-Rong Wang *Department of Otolaryngology, the First Hospital of Wuhan, Wuhan, 430022, China. 117248994@qq.com.
Hong-Fei Zhu *Department of Anesthesiology, Hubei Provincial Hospital of Traditional Chinese Medicine, Wuhan, 430061, China.
Yong Zhu *Department of General Surgery, Hubei Provincial Hospital of Traditional Chinese Medicine, Wuhan, 430061, China.
Hubei Provincial Hospital of Traditional Chinese Medicine · CNWuhan No.1 Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

MiRNAs are integral for maintaining immune homeostasis and self-tolerance. In this study, qPCR analyses were performed to determine which miRNAs play an important role in wound healing. Next, an experiment in a model of wound healing was performed, and histology, mRNA expression and T-cell subpopulations in wound tissue were analyzed. The accelerated experiments were performed by local injection of either rIL-17A and/or rIL-9 after wound healing. In vitro, the differentiation of Th17/Th9 in miR-155

Indexed as

Wound HealingAnimalsCell DifferentiationCytokinesDisease Models, AnimalGene Expression ProfilingMaleMiceMice, KnockoutMicroRNAsTh17 CellsT-Lymphocytes, Helper-InducerUp-RegulationCytokinesMicroRNAsMirn155 microRNA, mouseC-mafIL-17AIL-9miR155T cellswound healing

Identifiers

PMID31845227
OpenAlexW2996746624

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.