Evidence map›Paper›PMID 31845213›Full record

ArticleDrugs - real world outcomes2020

Drug Prescription in Older Swiss Men and Women Followed in Family Medicine.

David Schnegg, Nicolas Senn, Olivier Bugnon, Joëlle Schwarz, Yolanda Mueller

Registry-linked trialAbstract read
In one paragraph

Article in Drugs - real world outcomes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02618291 (Efficacy of a an Active Geriatric Evaluation), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02618291 nacompletednot on this map

Efficacy of a an Active Geriatric Evaluation (AGE Tool) for Geriatric Syndromes to Prevent Functional Decline in Elderly Patients in Family Medicine: a Pragmatic Cluster Randomized Trial

TypeinterventionalSponsorUniversity of LausanneRan2016 to 2020Enrolled429ConditionsGeriatric Syndrome, Functional AbilityArmsActive Geriatric Evaluation (AGE tool), Usual care
3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Observational
  2. Observational
  3. Article
  4. Article
  5. Article
  6. Use of Potentially Inappropriate Medications in Older Allogeneic Hematopoietic Cell Transplantation Recipients.Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

David SchneggUniversity of Lausanne, Lausanne, Switzerland.
Nicolas SennDepartment of Family Medicine/Center for Primary Care and Public Health (Unisanté), University of Lausanne, Lausanne, Switzerland.ORCID http://orcid.org/0000-0002-9986-3249
Olivier BugnonDepartment of Family Medicine/Center for Primary Care and Public Health (Unisanté), University of Lausanne, Lausanne, Switzerland.ORCID http://orcid.org/0000-0003-2249-1245
Joëlle SchwarzDepartment of Family Medicine/Center for Primary Care and Public Health (Unisanté), University of Lausanne, Lausanne, Switzerland.ORCID http://orcid.org/0000-0002-0992-3165
Yolanda MuellerDepartment of Family Medicine/Center for Primary Care and Public Health (Unisanté), University of Lausanne, Lausanne, Switzerland. Yolanda.mueller@unisante.ch.ORCID http://orcid.org/0000-0002-8861-4538

Funding

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung 32003B_159863/1
6 · The paper itself

Abstract

backgroundWe sought to estimate the prevalence of polypharmacy, the most prevalent drug classes involved, and the prevalence and type of potentially inappropriate prescribing among older male and female patients in family medicine.

methodsWe conducted a secondary analysis of baseline data from a pragmatic cluster-randomised trial on the efficacy of a screening and management tool for geriatric syndromes among older community-dwelling patients (aged ≥ 75 years) included by 42 family physicians. Information on drug prescription and clinical diagnoses (International Classification of Primary Care-2nd Edition [ICPC-2] coded) were extracted manually from medical records. The prevalence of polypharmacy, defined as the use of at least five permanent oral or parenteral drugs, and of potentially inappropriate medications (PIMs), identified according to 2015 updated Beers criteria, were compared between men and women.

resultsWe included 429 patients (269 women and 160 men; mean age 82.9 and 81.8 years, respectively). Polypharmacy was found in 59.9% of them. Analgesics, antithrombotic agents and agents acting on the renin-angiotensin system were the most frequently prescribed drug categories. Three-quarters of patients (76.7%) were prescribed at least one PIM according to Beers criteria, without difference by sex/gender (p = 0.760). The most frequent PIMs were proton-pump inhibitors used for > 8 weeks, diuretics, benzodiazepines, aspirin for primary prevention, and chronic use of non-steroidal anti-inflammatory drugs. Prescription patterns markedly differed by sex/gender, but the number and patterns of inappropriate prescriptions were comparable overall.

interpretationBoth polypharmacy and PIMs were very common in older patients followed regularly in family medicine in Switzerland. Interestingly, most PIMs involved only a limited number of medication classes.

trial registrationClinicaltrials.gov NCT02618291.

Identifiers

PMID31845213
PMCPMC7060976

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