Evidence map›Paper›PMID 31844995›Full record

ArticleEJNMMI physics2019

Reproducibility of compartmental modelling of

Laurence D Vass, Sarah Lee, Frederick J Wilson, Marie Fisk, Joseph Cheriyan, Ian Wilkinson

Abstract read
In one paragraph

Article in EJNMMI physics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Consensus Recommendations on the Use ofJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Laurence D VassExperimental Medicine and Immunotherapeutics, Department of Medicine, Addenbrookes Hospital, Cambridge, UK. ldv22@medschl.cam.ac.uk.
Sarah LeeAmallis Consulting LTD, London, UK.
Frederick J WilsonGSK R &D, Brentford, UK.
Marie FiskExperimental Medicine and Immunotherapeutics, Department of Medicine, Addenbrookes Hospital, Cambridge, UK.
Joseph CheriyanExperimental Medicine and Immunotherapeutics, Department of Medicine, Addenbrookes Hospital, Cambridge, UK.
Ian WilkinsonExperimental Medicine and Immunotherapeutics, Department of Medicine, Addenbrookes Hospital, Cambridge, UK.

Funding

British Heart Foundation FS/12/8/29377
6 · The paper itself

Abstract

introductionCompartmental modelling is an established method of quantifying

methodsRetrospective subject data were obtained from the EVOLVE observational study: Ten COPD patients (age =66±9; 8M/2F), 10 α

resultsThe initial agreement on a subject level was poor: Bland-Altman coefficients of reproducibility for K

conclusionsDespite similar methodology, differences in implementation can lead to disparate results in the outcome parameters. When reporting the outcomes of lung compartmental modelling, we recommend the inclusion of the details of ROI methodology, input function fitting and time delay estimation to improve reproducibility.

Indexed as

BiomarkersChronic obstructiveFluorodeoxyglucose F18Kinetic modellingLung inflammationPositron emission tomography computed tomographyPulmonary diseaseReproducibility of results

Identifiers

PMID31844995
PMCPMC6915187

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.