ArticleJournal of current ophthalmology2019
Comparison between patching and interactive binocular treatment in amblyopia: A randomized clinical trial.
Article in Journal of current ophthalmology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 6 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 6 syntheses or guidelines pooled it, 27 citations in OpenAlex.
- Research hotspots and trends of amblyopia treatment from 2015 to 2025: a bibliometric analysis.Frontiers in neuroscience · 2025Pooled it
- Binocular treatment for amblyopia: a systematic review.International ophthalmology · 2024Pooled it
- Computer-Assisted Visual Training in Children and Adolescents with Developmental Visual Disorders.Deutsches Arzteblatt international · 2023Pooled it
- Binocular versus standard occlusion or blurring treatment for unilateral amblyopia in children aged three to eight years.The Cochrane database of systematic reviews · 2022Pooled it
- Pooled it
- "OCT based retinal changes in amblyopia: A systematic review".Journal of optometryPooled it
- Video Game-Based Interventions for Visual Rehabilitation in Childhood Amblyopia: A Systematic Review and Meta-Analysis.Children (Basel, Switzerland) · 2026Review
- Short-term amblyopic eye deprivation boosts the binocular intermodulation in anisometropic amblyopia.Frontiers in neuroscience · 2026Article
- Binocular Approaches in Amblyopia Treatment Based on Dichoptic StimulationTurkish journal of ophthalmology · 2025Review
- Comparative effectiveness of gamified binocular treatment versus conventional patching for amblyopia: a randomized clinical trial.Frontiers in medicine · 2025Article
- Comparison of epidemiologic factors and eye manifestations of twin children with controls.BMC ophthalmology · 2023Article
- Long-Term Efficacy of the Combination of Active Vision Therapy and Occlusion in Children with Strabismic and Anisometropic Amblyopia.Children (Basel, Switzerland) · 2022Article
- Factors Affect the Eradication Rate ofInfection and drug resistance · 2022Article
- Current Management of Amblyopia with New Technologies for Binocular Treatment.Vision (Basel, Switzerland) · 2021Review
- Emerging therapies for amblyopia.Seminars in ophthalmology · 2021Article
- A Randomized Clinical Trial Comparing Eyetronix Flicker Glass and Patching for Treatment of Amblyopia in Children Reveals Similar Improvements in Vision.Frontiers in neuroscience · 2021Article
- Comparison between binocular therapy and patching for treatment of amblyopia: a meta-analysis of randomised controlled trials.BMJ open ophthalmology · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo compare the effect of amblyopia therapy on cases who received interactive binocular treatment (I-BiT™) with those who received standard patching of the dominant eye with placebo I-BiT™.
methodsIn this randomized clinical trial, 38 unilateral amblyopic children (3-10 years old) were studied. All unilateral amblyopic children who had best corrected visual acuity (BCVA) worse than 0.30 logMAR or a difference of two Snellen lines of BCVA between their two eyes were included, and children who did not complete at least 75% of amblyopia treatment were excluded from this study. Eventually, a total of 19 and 21 subjects were included in case and control groups, respectively. Cases played I-BiT™ games, while controls had standard patch therapy and played with placebo I-BiT™ games, both for one month. All subjects were examined at baseline and after one-month therapy.
resultsBCVA improved significantly in both groups after one-month treatment (case:
conclusionsI-BiT™ game and patching with placebo game had similar BCVA improvement in amblyopic children after one-month treatment. It is suggested to conduct further randomized clinical trials with a larger sample size and longer duration of study and assessment of its recurrence.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.