Evidence map›Paper›PMID 31844718›Full record

ArticleHeliyon2019

LncRNAs act as prognostic biomarkers in bladder carcinoma: A meta-analysis.

Yucheng Zhong, Yeshen Zhang, Huan Li, Wenmin Ma

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Heliyon, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yucheng ZhongAssisted Reproductive Technology Center, Foshan Maternity and Children's Healthcare Hospital Affiliated to Southern Medical University, Foshan, 528000, China.
Yeshen ZhangSchool of Clinical Medicine, Guangdong Pharmaceutical University, Guangzhou, 510006, China.
Huan LiAssisted Reproductive Technology Center, Foshan Maternity and Children's Healthcare Hospital Affiliated to Southern Medical University, Foshan, 528000, China.
Wenmin MaAssisted Reproductive Technology Center, Foshan Maternity and Children's Healthcare Hospital Affiliated to Southern Medical University, Foshan, 528000, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeIncreasing studies have shown that different kinds of lncRNAs play key role in the development of multiple carcinomas. Therefore, we conducted a meta-analysis to investigate an association between the expression level of lncRNAs and the prognosis of bladder cancer (death or other clinical outcomes).

methodsA systematic literature search was performed by using PubMed. Twenty-four studies were included in the meta-analysis based on the inclusion and exclusion criteria. In total, there are 1652 independent participants.

resultsThe result showed that high expression levels of lncRNAs were demonstrated to be associated with poor overall survival (OS) (HR = 2.33, 95%CI: 1.51-2.39,

conclusionIn conclusion, high expression levels of lncRNAs were demonstrated to be associated with poor OS and positive LNM, and lncRNAs might be potential prognostic markers in bladder cancer.

Indexed as

Bladder carcinomaCancer researchCell biologyLncRNAMeta-analysisMolecular biologyOncologyPrognosisUrology

Identifiers

PMID31844718
PMCPMC6895706

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.