ArticleScience advances2019
MiR-23~27~24-mediated control of humoral immunity reveals a TOX-driven regulatory circuit in follicular helper T cell differentiation.
Open access · goldAbstract read
In one paragraph
Article in Science advances, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 16% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.
- MicroRNAs in the regulation of Th17/Treg homeostasis and their potential role in uveitis.Frontiers in genetics · 2022Pooled it
- Circulating microRNAs miR-21-5p, miR-23a-3p and miR-26a-5p reflect clinical and molecular features of aging.Scientific reports · 2025Article
- Recent advances of miR-23 in human diseases and growth development.Non-coding RNA research · 2025Review
- Exploring the impact of gut microbiota-mediated regulation of exosomal miRNAs from bone marrow mesenchymal stem cells on the regulation of bone metabolism.Stem cell research & therapy · 2025Article
- TOX, through a glass, darkly.Frontiers in immunology · 2025Review
- Oligoclonal CD4Communications biology · 2024Article
- Elucidation of how the Mir-23-27-24 cluster regulates development and aging.Experimental & molecular medicine · 2024Review
- Adverse clinical outcomes and immunosuppressive microenvironment of RHO-GTPase activation pattern in hepatocellular carcinoma.Journal of translational medicine · 2024Article
- Studies on the role of non-coding RNAs in controlling the activity of T cells in asthma.Non-coding RNA research · 2023Review
- TOX regulates T lymphocytes differentiation and its function in tumor.Frontiers in immunology · 2023Review
- MicroRNA-23a-3p promotes macrophage M1 polarization and aggravates lipopolysaccharide-induced acute lung injury by regulating PLK1/STAT1/STAT3 signalling.International journal of experimental pathology · 2022Article
- The TOX subfamily: all-round players in the immune system.Clinical and experimental immunology · 2022Review
- Regulatory roles of MicroRNA in shaping T cell function, differentiation and polarization.Seminars in cell & developmental biology · 2022Review
- Aged bone matrix-derived extracellular vesicles as a messenger for calcification paradox.Nature communications · 2022Article
- N6-methyladenosine-related microRNAs risk model trumps the isocitrate dehydrogenase mutation status as a predictive biomarker for the prognosis and immunotherapy in lower grade gliomas.Exploration of targeted anti-tumor therapy · 2022Article
- Emerging Advances of Non-coding RNAs and Competitive Endogenous RNA Regulatory Networks in Asthma.Bioengineered · 2021Review
- Cell-intrinsic and -extrinsic roles of miRNAs in regulating T cell immunity.Immunological reviews · 2021Review
- Advancing to the era of cancer immunotherapy.Cancer communications (London, England) · 2021Review
- Single-nucleotide polymorphisms in 3'-untranslated region inducible costimulator gene and the important roles of miRNA in alopecia areata.Skin health and disease · 2021Article
- miR-23a/b suppress cGAS-mediated innate and autoimmunity.Cellular & molecular immunology · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
21 authors at 7 institutions in 6 countries.
Cheng-Jang WuDivision of Biological Sciences, University of California, San Diego, La Jolla, CA 92093, USA.ORCID 0000-0002-7640-5915
Sunglim ChoDivision of Biological Sciences, University of California, San Diego, La Jolla, CA 92093, USA.ORCID 0000-0003-3109-0216
Hsi-Yuan HuangDepartment of Laboratory Medicine, China Medical University Hospital, China Medical University, Taichung, Taiwan.
Chun-Hao LuDepartment of Microbiology and Immunology, Graduate Institute of Biomedical Sciences, College of Medicine, Chang Gung University, Tao-Yuan, Taiwan.
Jasmin RussDivision of Biological Sciences, University of California, San Diego, La Jolla, CA 92093, USA.
Leilani O CruzDivision of Biological Sciences, University of California, San Diego, La Jolla, CA 92093, USA.ORCID 0000-0003-4734-3855
Flavia Franco da CunhaDivision of Biological Sciences, University of California, San Diego, La Jolla, CA 92093, USA.ORCID 0000-0001-8209-7421
Mei-Chi ChenDivision of Biological Sciences, University of California, San Diego, La Jolla, CA 92093, USA.ORCID 0000-0002-9984-3459
Ling-Li LinDivision of Biological Sciences, University of California, San Diego, La Jolla, CA 92093, USA.
Lindsey M WarnerDivision of Biological Sciences, University of California, San Diego, La Jolla, CA 92093, USA.ORCID 0000-0002-4258-7271
Hsin-Kai LiaoGene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, CA 92037, USA.
Daniel T UtzschneiderDivision of Biological Sciences, University of California, San Diego, La Jolla, CA 92093, USA.
Sara QuonDivision of Biological Sciences, University of California, San Diego, La Jolla, CA 92093, USA.ORCID 0000-0003-3860-3491
Jacqueline BernerDivision of Animal Physiology and Immunology, School of Life Sciences Weihenstephan, Technical University of Munich, 85354 Freising, Germany.
Niels Olsen Saraiva CamaraDepartment of Nephrology, Federal University of Sao Paulo, Sao Paulo, Brazil.
Dietmar ZehnDivision of Animal Physiology and Immunology, School of Life Sciences Weihenstephan, Technical University of Munich, 85354 Freising, Germany.
Juan Carlos Izpisua BelmonteGene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, CA 92037, USA.ORCID 0000-0003-0557-8875
Li-Chen ChenDivision of Allergy, Asthma, and Rheumatology, Department of Pediatrics, Chang Gung Memorial Hospital, Tao-Yuan, Taiwan.
Shiang-Fu HuangDepartment of Otolaryngology, Head and Neck Surgery, Chang Gung Memorial Hospital and Department of Public Health, Chang Gung University, Tao-Yuan, Taiwan.ORCID 0000-0003-3582-9938
Ming-Ling KuoDepartment of Microbiology and Immunology, Graduate Institute of Biomedical Sciences, College of Medicine, Chang Gung University, Tao-Yuan, Taiwan.
Li-Fan LuDivision of Biological Sciences, University of California, San Diego, La Jolla, CA 92093, USA.ORCID 0000-0002-9727-0036
University of California San Diego · USChang Gung University · TWSalk Institute for Biological Studies · USTechnical University of Munich · DEChang Gung Memorial Hospital · TWChina Medical University · TWUniversidade de São Paulo · BR
Funding
Role of microRNAs in regulatory T cell-mediated immunological tolerance and T celR01AI108651 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI LU, LI-FAN · 2014 to 2024
$4.0MFunction of microRNAs in controlling regulatory T cell biologyR00AI089935 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI LU, LI-FAN · 2012 to 2013
$493kThe role of SOCS1 repression by miR-155 in regulating immune responsivenessR21AI103646 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI LU, LI-FAN · 2013 to 2014
$426kRole of miR-146a at the interface between T and B cell immunityR21AI123782 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI LU, LI-FAN · 2016 to 2017
$420kFunction of microRNAs in controlling regulatory T cell biologyK99AI089935 · NIAID · SLOAN-KETTERING INST CAN RESEARCH · PI LU, LI-FAN · 2011 to 2011
$94kNIAID NIH HHS K99 AI089935NIAID NIH HHS R00 AI089935NIAID NIH HHS R01 AI108651NIAID NIH HHS R21 AI103646NIAID NIH HHS R21 AI123782
Abstract
Follicular helper T (T
Indexed as
AnimalsCell DifferentiationGene Expression Regulation, DevelopmentalHigh Mobility Group ProteinsHumansImmunity, HumoralLymphocyte ActivationMiceMicroRNAsProto-Oncogene Proteins c-bcl-6Signal TransductionT-LymphocytesT-Lymphocytes, Helper-InducerBCL6 protein, humanHigh Mobility Group ProteinsMicroRNAsMirn23b microRNA, mouseMirn24 microRNA, mouseMirn27 microRNA, mouseProto-Oncogene Proteins c-bcl-6TOX protein, human
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.