Evidence map›Paper›PMID 31844538›Full record

ArticleMaternal health, neonatology and perinatology2019

Induction of labor and early-onset Sepsis guidelines: impact on NICU admissions in Erie County, NY.

Vikramaditya Dumpa, Indira Avulakunta, James Shelton, Taechin Yu, Satyan Lakshminrusimha

Abstract read
In one paragraph

Article in Maternal health, neonatology and perinatology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Vikramaditya Dumpa1Division of Neonatology, Department of Pediatrics, NYU Winthrop Hospital, 259 First St, Mineola, New York, 11501 USA.ORCID 0000-0002-1112-8590
Indira AvulakuntaDepartment of Pediatrics, Brookdale University Hospital and Medical, 1 Brookdale Plaza, Brooklyn, New York, 11212 USA.
James SheltonDepartment of Obstetrics and Gynecology, Oishei Children's Hospital, 1001 Main St, Buffalo, New York, 14203 USA.
Taechin Yu4Department of Obstetrics and Gynecology, Holy Redeemer Health System, 667 Old Welsh Rd, Huntingdon Valley, PA 19006 USA.
Satyan LakshminrusimhaDepartment of Pediatrics, UC Davis Children's Hospital, 2516 Stockton Blvd, Sacramento, California, 95817 USA.

Funding

Optimal Oxygenation in Neonatal Lung InjuryR01HD072929 · NICHD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Satyanarayana Lakshminrusimha · 2012 to 2026
$5.4M
NICHD NIH HHS R01 HD072929
6 · The paper itself

Abstract

backgroundElective delivery prior to term gestation is associated with adverse neonatal outcomes. The impact of American College of Obstetricians and Gynecologists (ACOG) guidelines recommending against induction of labor (IOL) < 39 weeks' postmenstrual age (PMA) on the frequency of early-term births and NICU admissions in Erie County, NY was evaluated in this study.

methodsThis is a population-based retrospective comparison of all live births and NICU admissions in Erie County, NY between pre-and post-ACOG IOL guideline epochs (2005-2008 vs. 2011-2014). Information on early-term, full/late/post-term births and NICU admissions was obtained. A detailed chart analysis of indications for admission to the Regional Perinatal Center was performed.

resultsDuring the 2005-2008 epoch, early-term births constituted 27% (11,968/44,617) of live births. The NICU admission rate was higher for early-term births (1134/11968 = 9.5%) compared to full/late/post-term (1493/27541 = 5.4%).In the 2011-2014 epoch, early-term births decreased to 23% (10,286/44,575) of live births. However, NICU admissions for early-term (1072/10286 = 10.4%) and full/late/post-term births (1892/29508 = 6.4%) did not decrease partly due to asymptomatic infants exposed to maternal chorioamnionitis admitted for empiric antibiotic therapy as per revised early-onset sepsis guidelines.

conclusionsACOG recommendations against elective IOL or cesarean delivery < 39 weeks PMA were rapidly translated to clinical practice and decreased early-term births in Erie County, NY. This decrease did not translate to reduced NICU admissions partly due to increased NICU admissions for empiric antibiotic therapy.

Indexed as

ACOG guidelinesEarly-onset sepsisEarly-termInduction of labor

Identifiers

PMID31844538
PMCPMC6894216

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.