Evidence map›Paper›PMID 31844485›Full record

ArticleThe journal of physical chemistry. C, Nanomaterials and interfaces2019

What Does Nanoparticle Stability Mean?

Hoa T Phan, Amanda J Haes

Abstract read
In one paragraph

Article in The journal of physical chemistry. C, Nanomaterials and interfaces, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 102 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
102citing papers in PubMed, 1 pooled it
12.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

102 citing papers in PubMed, 1 synthesis or guideline pooled it, 431 citations in OpenAlex.

  1. Nanoformulations in epilepsy therapy - a systematic review of emerging strategies in status epilepticus.Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences · 2025
    Pooled it
  2. Article
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  6. Review
  7. Gold nanoparticles incorporating rutin hydrate for targeting oxidative stress-driven neurodegeneration.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2026
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42 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Hoa T PhanDepartment of Chemistry, University of Iowa, Iowa City, Iowa 52242, United States.
Amanda J HaesDepartment of Chemistry, University of Iowa, Iowa City, Iowa 52242, United States.
University of Iowa · US

Funding

Rapid Uranium Sensors to Minimize Health Impacts in the Navajo NationR01ES027145 · NIEHS · UNIVERSITY OF IOWA · PI CERRATO, JOSE MANUEL, CWIERTNY, DAVID MICHAEL · 2017 to 2020
$1.3M
NIEHS NIH HHS R01 ES027145
6 · The paper itself

Abstract

The term "nanoparticle stability" is widely used to describe the preservation of a particular nanostructure property ranging from aggregation, composition, crystallinity, shape, size, and surface chemistry. As a result, this catch-all term has various meanings, which depend on the specific nanoparticle property of interest and/or application. In this feature article, we provide an answer to the question, "What does nanoparticle stability mean?". Broadly speaking, the definition of nanoparticle stability depends on the targeted size dependent property that is exploited and can only exist for a finite period of time given all nanostructures are inherently thermodynamically and energetically unfavorable relative to bulk states. To answer this question specifically, however, the relationship between nanoparticle stability and the physical/chemical properties of metal/metal oxide nanoparticles are discussed. Specific definitions are explored in terms of aggregation state, core composition, shape, size, and surface chemistry. Next, mechanisms of promoting nanoparticle stability are defined and related to these same nanoparticle properties. Metrics involving both kinetics and thermodynamics are considered. Methods that provide quantitative metrics for measuring and modeling nanoparticle stability in terms of core composition, shape, size, and surface chemistry are outlined. The stability of solution-phase nanoparticles are also impacted by aggregation state. Thus, collision and DLVO theories are discussed. Finally, challenges and opportunities in understanding what nanoparticle stability means are addressed to facilitate further studies with this important class of materials.

Identifiers

PMID31844485
PMCPMC6913534
OpenAlexW2945501847

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.