ArticleNature biotechnology2020
The industrial yeast Pichia pastoris is converted from a heterotroph into an autotroph capable of growth on CO
Article in Nature biotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 117 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
117 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A Systematic Review of the Potential of Pichia pastoris (Komagataella phaffii) as an Alternative Host for Biologics Production.Molecular biotechnology · 2024Pooled it
- Reprogramming energy system for growth and bioproduction from CO₂ and methanol in Escherichia coli.Nature communications · 2026Article
- Random mutagenesis platform for accelerated genome evolution (RAMPAGE) ofEngineering microbiology · 2026Article
- Repair of DNA and protein damages caused by formaldehyde improves methanol assimilation.Fundamental research · 2026Article
- Yeast-driven biomanufacturing in space: synergizing cellular agriculture for sustainable extraterrestrial habitats.NPJ microgravity · 2026Review
- Synthetic Biology of Plants and Microbes for Agriculture, Environment, and Future Applications.Chemical reviews · 2026Review
- Adaptive Laboratory Evolution of Pichia pastoris by Serial Batch Cultivation.Methods in molecular biology (Clifton, N.J.) · 2026Article
- Integrating resource utilization and bioregenerative life support systems for sustainable space exploration.Frontiers in microbiology · 2026Review
- Engineering de novo formatotrophy in the non-model yeastNature synthesis · 2026Article
- Biomanufacture of diverse chemicals in yeast.Innovation (Cambridge (Mass.)) · 2025Review
- Key Technologies of Synthetic Biology in Industrial Microbiology.Microorganisms · 2025Review
- Synthetic autotrophic yeast enables high itaconic acid production from COGreen chemistry : an international journal and green chemistry resource : GC · 2025Article
- Engineering COInternational journal of molecular sciences · 2025Article
- A blueprint for designing the next-generation of synthetic CNature communications · 2025Review
- Industrial applicability of enzymatic and whole-cell processes for the utilization of C1 building blocks.Nature communications · 2025Review
- Convergent expansions of keystone gene families drive metabolic innovation in Saccharomycotina yeasts.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Carbon sequestration pathways in microorganisms: Advances, strategies, and applications.Engineering microbiology · 2025Review
- Advancing yeast metabolism for a sustainable single carbon bioeconomy.FEMS yeast research · 2025Review
- Perspectives on current and future yeast technologies for ethanol-based biofuels and bioproducts.FEMS yeast research · 2025Review
- The genetically encoded biosensor HyPer7 enables in-line monitoring of H2O2 accumulation dynamics in the methylotrophic yeast Komagataella phaffii.FEMS yeast research · 2025Article
57 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
The methylotrophic yeast Pichia pastoris is widely used in the manufacture of industrial enzymes and pharmaceuticals. Like most biotechnological production hosts, P. pastoris is heterotrophic and grows on organic feedstocks that have competing uses in the production of food and animal feed. In a step toward more sustainable industrial processes, we describe the conversion of P. pastoris into an autotroph that grows on CO
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.