Evidence map›Paper›PMID 31844293›Full record

ArticleNature biotechnology2020

Electrical recognition of the twenty proteinogenic amino acids using an aerolysin nanopore.

Hadjer Ouldali, Kumar Sarthak, Tobias Ensslen, Fabien Piguet, Philippe Manivet, Juan Pelta, Jan C Behrends, Aleksei Aksimentiev, Abdelghani Oukhaled

Open access · greenAbstract read
In one paragraph

Article in Nature biotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 194 papers.

0numbers the graph read from it
0cells of the map it votes in
194citing papers in PubMed
23.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

194 citing papers in PubMed, 459 citations in OpenAlex.

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  16. Biosensing With Nanofluidics.Exploration (Beijing, China) · 2026
    Review
  17. Nanopore event detection in a simple and adaptive way.bioRxiv : the preprint server for biology · 2026
    Article
  18. Article
  19. Review
  20. Article

134 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 3 countries.

Hadjer OuldaliLAMBE UMR 8587, Université de Cergy-Pontoise, CNRS, CEA, Université Paris-Seine, Cergy-Pontoise, France.
Kumar SarthakCenter for Biophysics and Quantitative Biology, University of Illinois at Urbana-Champaign, Urbana, IL, USA.
Tobias EnsslenLaboratory for Membrane Physiology and Technology, Department of Physiology, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Fabien PiguetLAMBE UMR 8587, Université de Cergy-Pontoise, CNRS, CEA, Université Paris-Seine, Cergy-Pontoise, France.
Philippe ManivetAPHP, GHU APHP.Nord, DMU BioGem, Hôpital Lariboisière, BIOBANK Lariboisière Department BB-0033-00064, Plateforme de BioPathologie et de Technologies Innovantes en Santé, Paris, France.
Juan PeltaLAMBE UMR 8587, Université d'Evry-Val-d'Essonne, CNRS, CEA, Université Paris-Saclay, Evry, France.
Jan C BehrendsLaboratory for Membrane Physiology and Technology, Department of Physiology, Faculty of Medicine, University of Freiburg, Freiburg, Germany.ORCID http://orcid.org/0000-0001-9686-7263
Aleksei AksimentievCenter for Biophysics and Quantitative Biology, University of Illinois at Urbana-Champaign, Urbana, IL, USA. aksiment@illinois.edu.ORCID http://orcid.org/0000-0002-6042-8442
Abdelghani OukhaledLAMBE UMR 8587, Université de Cergy-Pontoise, CNRS, CEA, Université Paris-Seine, Cergy-Pontoise, France. abdelghani.oukhaled@u-cergy.fr.ORCID http://orcid.org/0000-0002-9675-6747
Centre National de la Recherche Scientifique · FRUniversity of Freiburg · DEUniversity of Illinois Urbana-Champaign · USInserm · FR

Funding

WHOLE CELL SIMULATIONP41GM104601 · NIGMS · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI TAJKHORSHID, EMAD · 2012 to 2021
$19.0M
Plasmonic nanopores for trapping, controlled motion and sequencing of DNAR01HG007406 · NHGRI · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI AKSIMENTIEV, ALEKSEI · 2013 to 2016
$2.4M
NHGRI NIH HHS R01 HG007406NIGMS NIH HHS P41 GM104601
6 · The paper itself

Abstract

Efforts to sequence single protein molecules in nanopores

Indexed as

ElectricityNanoporesAmino AcidsBacterial ToxinsMolecular Dynamics SimulationPeptidesPore Forming Cytotoxic ProteinsProteinsaerolysinAmino AcidsBacterial ToxinsPeptidesPore Forming Cytotoxic ProteinsProteins

Identifiers

PMID31844293
PMCPMC7008938
OpenAlexW2995162887

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.