Evidence map›Paper›PMID 31844137›Full record

ArticleBone marrow transplantation2020

Haploidentical transplantation and posttransplant cyclophosphamide for treating aplastic anemia patients: a report from the EBMT Severe Aplastic Anemia Working Party.

Pedro H Prata, Dirk-Jan Eikema, Boris Afansyev, Paul Bosman, Frans Smiers, José L Diez-Martin, Celso Arrais-Rodrigues, Yener Koc, Xavier Poiré, Anne Sirvent and 21 more

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Bone marrow transplantation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 2 pooled it
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 2 syntheses or guidelines pooled it, 74 citations in OpenAlex.

  1. Guideline
  2. Pooled it
  3. Trial
  4. Article
  5. Article
  6. Future directions in transplantation for aplastic anemia.Hematology. American Society of Hematology. Education Program · 2025
    Review
  7. Review
  8. Article
  9. Conditioning Regimen Options.Advances in experimental medicine and biology · 2025
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Allogeneic bone marrow transplantation for aplastic anemia.International journal of hematology · 2024
    Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

31 authors at 18 institutions in 14 countries.

Pedro H PrataHematology-Transplantation Department, Saint-Louis Hospital, Paris, France. pedrohenrique.delimaprata@aphp.fr.ORCID http://orcid.org/0000-0003-0235-7890
Dirk-Jan EikemaEBMT Statistical Unit, Leiden, The Netherlands.
Boris AfansyevFirst State Pavlov Medical University, St Petersburg, Russia.
Paul BosmanEBMT Data Office, Leiden, The Netherlands.
Frans SmiersLeiden University Hospital, Leiden, The Netherlands.
José L Diez-MartinDepartamento de Medicina, Gregorio Maranon G.U. Hospital, Instituto de Investigación Sanitaria Gregorio Marañón, Universidad Complutense, Madrid, Spain.
Celso Arrais-RodriguesSírio-Libanês Hospital, Sao Paulo, Brazil.
Yener KocMedical Park Hospitals, Antalya, Turkey.
Xavier PoiréClinique Universitaire St. Luc, Brussels, Belgium.ORCID http://orcid.org/0000-0003-1897-0227
Anne SirventCHU Lapeyronie, Montpellier, France.
Nicolaus KrögerUniversity Hospital Eppendorf, Hamburg, Germany.
Fulvio PortaOspedale dei Bambini Spedali Civili, Brescia, Italy.
Wolfgang HolterSt. Anna Kinderspital, Vienna, Austria.
Adrian BloorChristie NHS Trust Hospital, Manchester, UK.
Charlotte JubertGroupe Hospitalier Pellegrin-Enfants, Bordeaux, France.
Arnold GanserHannover Medical School, Hannover, Germany.
Alina TanaseFundeni Clinical Institute, Bucharest, Romania.
Anne-Lise MénardCentre Henri Becquerel, Rouen, France.
Pietro PioltelliOspedale San Gerardo, Monza, Italy.
José A Pérez-SimónHospital Universitario Virgen del Rocio, Sevilla, Spain.
Aloysius HoSingapore General Hospital, Singapore, Singapore.
Mahmoud AljurfKing Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia.
Nigel RussellNottingham University, Nottingham, UK.
Helene Labussiere-WalletCentre Hospitalier Lyon Sud, Lyon, France.
Tessa KerreGhent University Hospital, Ghent, Belgium.
Vanderson RochaSírio-Libanês Hospital, Sao Paulo, Brazil.
Gérard SociéHematology-Transplantation Department, Saint-Louis Hospital, Paris, France.ORCID http://orcid.org/0000-0002-2114-7533
Antonio RisitanoFederico II University of Naples, Naples, Italy.ORCID http://orcid.org/0000-0002-4744-5109
Carlo Dufour *Giannina Gaslini Children's Hospital, Genoa, Italy.
Régis Peffault de Latour *Hematology-Transplantation Department, Saint-Louis Hospital, Paris, France.
SAA WP of the EBMT
Azienda Ospedaliera San Gerardo · ITCliniques Universitaires Saint-Luc · BEFirst Pavlov State Medical University of St. Petersburg · RUGhent University Hospital · BEHôpital Saint-Louis · FRInserm · FRIstituto Giannina Gaslini · ITLeiden University · NLMedizinische Hochschule Hannover · DESingapore General Hospital · SGSt Anna Children's Hospital · ATUniversität Hamburg · DEUniversity of Nottingham · GBEuropean Society for Blood and Marrow Transplantation · NLHôpital Pellegrin · FRHospital General Universitario Gregorio Marañón · ESHospital Sírio-Libanês · BRInstitutul Clinic Fundeni · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the absence of an HLA-matched donor, the best treatment for acquired aplastic anemia patients refractory to immunosuppression is unclear. We collected and analyzed data from all acquired aplastic anemia patients who underwent a haploidentical transplantation with posttransplant cyclophosphamide in Europe from 2011 to 2017 (n = 33). The cumulative incidence of neutrophil engraftment was 67% (CI

Indexed as

Anemia, AplasticGraft vs Host DiseaseHematopoietic Stem Cell TransplantationCyclophosphamideEuropeHumansProspective StudiesTransplantation ConditioningTransplantation, HaploidenticalCyclophosphamide

Identifiers

PMID31844137
OpenAlexW2995620323

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.