ArticleScientific reports2019
Study on neuropathological mechanisms of primary monosymptomatic nocturnal enuresis in children using cerebral resting-state functional magnetic resonance imaging.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Brain microstructure in children with primary monosymptomatic nocturnal enuresis: a diffusion kurtosis imaging study.European journal of pediatrics · 2025Article
- Functional connectivity density of brain in children with primary nocturnal enuresis: results from a resting-state fMRI study.European child & adolescent psychiatry · 2025Article
- The Resting-State Activities of the Angular Gyrus and the Micturition Desire-Awakening Function in Children With and Without Enuresis.Brain and behavior · 2024Article
- The effect of screen time on the presentation and treatment of primary monosymptomatic nocturnal enuresis.BMC urology · 2023Article
- The atypical functional connectivity of Broca's area at multiple frequency bands in autism spectrum disorder.Brain imaging and behavior · 2022Article
- Altered resting-state functional connectivity of insula in children with primary nocturnal enuresis.Frontiers in neuroscience · 2022Article
- Altered Effective Connectivity of the Primary Motor Cortex in Transient Ischemic Attack.Neural plasticity · 2022Article
- The brain mechanism of awakening dysfunction in children with primary nocturnal enuresis based on PVT-NAc neural pathway: a resting-state fMRI study.Scientific reports · 2021Article
- Pathogenesis and brain functional imaging in nocturnal enuresis: A review.Experimental biology and medicine (Maywood, N.J.) · 2021Review
- Frequency-specific alterations of the resting-state BOLD signals in nocturnal enuresis: an fMRI Study.Scientific reports · 2021Article
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11 authors.
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Abstract
Primary monosymptomatic nocturnal enuresis (PMNE) is a heterogeneous disorder, which remains a difficult condition to manage due to lack of knowledge on the underlying pathophysiological mechanisms. Here we investigated the underlying neuropathological mechanisms of PMNE with functional MRI (fMRI), combining the amplitude of low frequency fluctuation (ALFF), regional homogeneity (ReHo), and seed-based functional connectivity (seed-based FC) analyses. Compared to the control group, PMNE group showed decreased ALFF value in the left medial orbital superior frontal gyrus (Frontal_Med_Orb_L), and increased ReHo value in the left superior occipital gyrus (Occipital_Sup_L). With left thalamus as the seed, PMNE group showed significantly decreased functional connectivity to the left medial superior frontal gyrus (Frontal_Sup_Medial_L). We conclude that these abnormal brain activities are probably important neuropathological mechanisms of PMNE in children. Furthermore, this study facilitated the understanding of underlying pathogenesis of PMNE and may provide an objective basis for the effective treatment.
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