Observational studyNature communications2019
IL-17
Open access · goldAbstract readObservational Study
In one paragraph
Observational study in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers, 2 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed, 2 pooled it
4.6field-weighted citation impact, top 4% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
65 citing papers in PubMed, 2 syntheses or guidelines pooled it, 97 citations in OpenAlex.
- The dual role of mTOR in multiple sclerosis pathophysiology: a systematic review.Journal of neurology · 2026Pooled it
- Pooled it
- Dimethyl fumarate treatment restrains the antioxidative capacity of T cells to control autoimmunity.Brain : a journal of neurology · 2021Trial
- Repopulation of T, B, and NK cells following alemtuzumab treatment in relapsing-remitting multiple sclerosis.Journal of neuroinflammation · 2020Trial
- Redox Imbalance in CD4+ T Cells of Relapsing-Remitting Multiple Sclerosis Patients.Oxidative medicine and cellular longevity · 2020Trial
- Fumarate and Its Esters: Physiology, Pathology, Molecular Mechanisms, Diseases, and Therapy.MedComm · 2026Review
- Selected Cytokines and Matrix Metalloproteinases in Pathogenesis and Treatment of Multiple Sclerosis.International journal of molecular sciences · 2026Review
- Rhoifolin Alleviates Ulcerative Colitis by Targeting NMNAT1 and Activating SIRT1-FOXO1 Signaling to Enhance ILC3s Effector Function.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Article
- Excessive reactive oxygen species attenuated IL-17 production in CD161Cell communication and signaling : CCS · 2026Article
- Reactive oxygen species (ROS) in cancer: from mechanism to therapeutic implications.Signal transduction and targeted therapy · 2026Review
- Fumarate and fumarate hydratase: an immunometabolite regulator of inflammation and diseases.Frontiers in immunology · 2026Review
- The combination of venetoclax with dimethyl fumarate synergistically induces apoptosis in AML cells by disrupting mitochondrial integrity through ROS accumulation.Cell death & disease · 2025Article
- Dimethyl fumarate reprograms cervical cancer cells to enhance antitumor immunity by activating mtDNA-cGAS-STING pathway.Journal of biomedical science · 2025Article
- Evaluating the Serum Level of ACTH and Investigating the Expression of miR-26a, miR-34a, miR-155-5p, and miR-146a in the Peripheral Blood Cells of Multiple Sclerosis Patients.Biochemical genetics · 2025Article
- Fecal Microbiota Transplantation Modulates Th17/Treg Balance via JAK/STAT Pathway in ARDS Rats.Advanced biology · 2025Article
- Acetyl 11-Keto Beta-Boswellic Acid Improves Neurological Functions in a Mouse Model of Multiple Sclerosis.Inflammation · 2025Article
- Annexin A1 is crucial during Toxoplasma gondii infection promoting the modulation of inflammation and intestinal and central nervous system barrier functions.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2025Article
- Targeting PD-1 and CD85j can restore intratumoral CD4Journal for immunotherapy of cancer · 2025Article
- The link between gut microbiota and multiple sclerosis from the perspective of barrier function.Frontiers in immunology · 2025Review
5 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
28 authors at 9 institutions in 7 countries.
Christina LückelInstitute for Medical Microbiology and Hospital Hygiene, University of Marburg, 35043, Marburg, Germany.
Felix PicardInstitute for Medical Microbiology and Hospital Hygiene, University of Marburg, 35043, Marburg, Germany.ORCID http://orcid.org/0000-0001-7624-4704
Hartmann RaiferInstitute for Medical Microbiology and Hospital Hygiene, University of Marburg, 35043, Marburg, Germany.
Lucia Campos CarrascosaInstitute for Medical Microbiology and Hospital Hygiene, University of Marburg, 35043, Marburg, Germany.
Anna GuralnikInstitute for Medical Microbiology and Hospital Hygiene, University of Marburg, 35043, Marburg, Germany.
Yajuan ZhangInstitute for Medical Microbiology and Hospital Hygiene, University of Marburg, 35043, Marburg, Germany.
Matthias KleinInstitute for Immunology, University Medical Center of the Johannes Gutenberg-University Mainz, 55131, Mainz, Germany.
Stefan BittnerDepartment of Neurology at the University Medical Center of the Johannes Gutenberg-University Mainz, 55131, Mainz, Germany.ORCID http://orcid.org/0000-0003-2179-3655
Falk SteffenDepartment of Neurology at the University Medical Center of the Johannes Gutenberg-University Mainz, 55131, Mainz, Germany.
Sonja MoosInstitute for Molecular Medicine, University Medical Center of the Johannes Gutenberg-University Mainz, 55131, Mainz, Germany.
Federico MariniInstitute of Medical Biostatistics, Epidemiology and Informatics (IMBEI), University Medical Center of the Johannes Gutenberg-University Mainz, 55131, Mainz, Germany.ORCID http://orcid.org/0000-0003-3252-7758
Renee GlouryThe Peter Doherty Institute for Infection and Immunity, Dept. of Microbiology and Immunology, University of Melbourne, Melbourne, VIC, 3000, Australia.
Florian C KurschusInstitute for Molecular Medicine, University Medical Center of the Johannes Gutenberg-University Mainz, 55131, Mainz, Germany.
Ying-Yin ChaoCenter for Translational Cancer Research TranslaTUM, Technical University of Munich, 81675, Munich, Germany.
Wilhelm BertramsInstitute for Lung Research, Universities of Giessen and Marburg Lung Center, Philipps-University Marburg, Member of the German Center for Lung Research (DZL), 35043, Marburg, Germany.
Veronika SexlInstitute of Pharmacology and Toxicology, University of Veterinary Medicine Vienna, 1210, Vienna, Austria.
Bernd SchmeckInstitute for Lung Research, Universities of Giessen and Marburg Lung Center, Philipps-University Marburg, Member of the German Center for Lung Research (DZL), 35043, Marburg, Germany.
Lynn BonettiDept. of Infection and Immunity, Experimental and Molecular Immunology, Luxembourg Institute of Health, Esch-sur-Alzette, L-4354, Luxembourg.
Melanie GrusdatDept. of Infection and Immunity, Experimental and Molecular Immunology, Luxembourg Institute of Health, Esch-sur-Alzette, L-4354, Luxembourg.
Michael LohoffInstitute for Medical Microbiology and Hospital Hygiene, University of Marburg, 35043, Marburg, Germany.
Christina E ZielinskiCenter for Translational Cancer Research TranslaTUM, Technical University of Munich, 81675, Munich, Germany.
Frauke ZippDepartment of Neurology at the University Medical Center of the Johannes Gutenberg-University Mainz, 55131, Mainz, Germany.ORCID http://orcid.org/0000-0002-1231-1928
Axel KalliesThe Peter Doherty Institute for Infection and Immunity, Dept. of Microbiology and Immunology, University of Melbourne, Melbourne, VIC, 3000, Australia.ORCID http://orcid.org/0000-0002-6312-6968
Dirk BrennerDept. of Infection and Immunity, Experimental and Molecular Immunology, Luxembourg Institute of Health, Esch-sur-Alzette, L-4354, Luxembourg.
Michael BergerThe Lautenberg Center for Immunology and Cancer Research, IMRIC, Faculty of Medicine, The Hebrew University, Jerusalem, 9112001, Israel.ORCID http://orcid.org/0000-0002-3469-0076
Tobias BoppInstitute for Immunology, University Medical Center of the Johannes Gutenberg-University Mainz, 55131, Mainz, Germany.ORCID http://orcid.org/0000-0002-3232-8065
Björn TackenbergCenter of Neuroimmunology, Dept. of Neurology, University of Marburg, 35043, Marburg, Germany.
Magdalena HuberInstitute for Medical Microbiology and Hospital Hygiene, University of Marburg, 35043, Marburg, Germany. magdalena.huber@staff.uni-marburg.de.
Philipps University of Marburg · DEJohannes Gutenberg University Mainz · DEGerman Center for Infection Research · DELuxembourg Institute of Health · LUThe University of Melbourne · AUGerman Center for Lung Research · DEHebrew University of Jerusalem · ILUniversity of Southern Denmark · DKUniversity of Veterinary Medicine Vienna · AT
Funding
No grant is acknowledged in the PubMed record.
Abstract
IL-17-producing CD8
Indexed as
AdolescentAdultAnimalsCD8-Positive T-LymphocytesDimethyl FumarateEncephalomyelitis, Autoimmune, ExperimentalFemaleHumansImmunosuppressive AgentsInterleukin-17Longitudinal StudiesMaleMiceMiddle AgedMultiple SclerosisTh17 CellsDimethyl FumarateImmunosuppressive AgentsInterleukin-17
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.