Evidence map›Paper›PMID 31843781›Full record

ArticleBMJ case reports2019

Refractory recurrent ocular graft versus host disease.

Emily Greenan, Elisabeth Vandenberghe, Conor C Murphy

Abstract readCase Reports
In one paragraph

Article in BMJ case reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Emily GreenanOphthalmology, Royal College of Surgeons in Ireland, Dublin, Ireland.
Elisabeth VandenbergheSt James's Hospital and Trinity College, Dublin 8, Ireland.
Conor C MurphyOphthalmology, Royal College of Surgeons in Ireland, Dublin, Ireland conorcmurphy@rcsi.ie.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ocular graft-versus-host disease (GVHD) is one of the most frequent and long-term complications affecting patients after haematopoietic stem cell transplantation. It is associated with significant morbidity and a marked reduction in quality of life. Although common, currently there are no widely accepted guidelines available for its management, and no suggested regime of treatment that is completely satisfactory. So far, prophylactic treatment strategies for ocular GVHD have yet to be developed and treatment is normally initiated based on symptoms often after permanent ocular tissue changes and surface damage has occurred. Here we describe a case of recurrent ocular GVHD and its associated complications that was highly refractory to treatment.

Indexed as

Dry Eye SyndromesFemaleGraft vs Host DiseaseHematopoietic Stem Cell TransplantationHumansQuality of LifeTreatment FailureVisual AcuityYoung Adultanterior chambereyehaematology (incl blood transfusion)malignant and benign haematology

Identifiers

PMID31843781
PMCPMC6936579

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.