Evidence map›Paper›PMID 31843772›Full record

ArticleBMJ case reports2019

Severe haemolytic disease of a newborn with variant D mimicking blocked-D phenomenon.

Soumya Das, Shamee Shastry, Poornima B Baliga

Open access · greenAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ case reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Soumya DasClinical Hematology and Medical Oncology, Malabar Cancer Center, Thalassery, Kerala, India.ORCID http://orcid.org/0000-0003-2589-8315
Shamee ShastryImmunohematology and Blood Transfusion, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, Udupi, Karnataka, India shameeshastry@gmail.com.ORCID http://orcid.org/0000-0001-9796-2326
Poornima B BaligaImmunohematology and Blood Transfusion, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, Udupi, Karnataka, India.
Manipal Academy of Higher Education · INMalabar Cancer Centre · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anti-D is still the most common antibody causing severe haemolytic disease of the fetus and newborn (HDFN). In a mother with a very high titer of anti-D, antibodies can coat and block the D antigens on the red blood cells of the newborn. This blocking phenomenon prevents agglutination of the D-positive red cells with the IgM anti-D typing reagent, giving false negative results. Here, we report the case of a newborn with variant D phenotype and severe HDFN, which mimicked the blocked-D phenomenon, which, at the first instance, confused both the treating clinicians and the transfusion service personnel.

Indexed as

AdultBlood Grouping and CrossmatchingErythroblastosis, FetalErythrocyte TransfusionFemaleHemolysisHumansInfant, NewbornMalePregnancyRh-Hr Blood-Group SystemRho(D) Immune GlobulinRh-Hr Blood-Group SystemRHO(D) antibodyRho(D) Immune Globulinhaematology (incl blood transfusion)materno-fetal medicineneonatal and paediatric intensive careobstetrics and gynaecologypregnancy

Identifiers

PMID31843772
PMCPMC6936407
OpenAlexW2995169855

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.