Evidence map›Paper›PMID 31842992›Full record

ArticleTrials2019

Breastfeeding success with the use of the inverted syringe technique for management of inverted nipples in lactating women: a study protocol for a randomized controlled trial.

Mona Nabulsi, Rayan Ghanem, Marlie Abou-Jaoude, Ali Khalil

Registry-linked trialOpen access · goldAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in Trials, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03529630 (Breastfeeding Success With the Use of the WHO Syringe Technique for Management of Inverted Nipples in Lactating Women), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03529630 nacompletednot on this map

Breastfeeding Success With the Use of the WHO Syringe Technique for Management of Inverted Nipples in Lactating Women: a Study Protocol for a Randomized Controlled Trial

TypeinterventionalSponsorAmerican University of Beirut Medical CenterRan2018 to 2020Enrolled54ConditionsBreastfeeding, Inverted NippleArmsInverted syringe
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Mona NabulsiDepartment of Pediatrics and Adolescent Medicine, Faculty of Medicine, American University of Beirut, Beirut, Lebanon. mn04@aub.edu.lb.ORCID http://orcid.org/0000-0001-7415-6436
Rayan GhanemDepartment of Obstetrics and Gynecology, Faculty of Medicine, American University of Beirut, Beirut, Lebanon.
Marlie Abou-JaoudeDepartment of Obstetrics and Gynecology, Faculty of Medicine, American University of Beirut, Beirut, Lebanon.
Ali KhalilDepartment of Obstetrics and Gynecology, Faculty of Medicine, American University of Beirut, Beirut, Lebanon.
American University of Beirut · LBAmerican University of Beirut Medical Center · LB

Funding

American University of Beirut MPP 11485.720.9999
6 · The paper itself

Abstract

backgroundBreastfeeding provides ideal infant nutrition, conferring several health benefits to children and their mothers. Women with inverted nipples, however, face difficulties that force them to prematurely terminate breastfeeding. Whereas available conservative measures for the correction of inverted nipples are of limited success, the use of an inverted syringe may be effective in achieving high rates of infant latching and exclusive breastfeeding. This technique, however, has not been investigated in a clinical trial. METHODS/

designThis open-label randomized controlled trial aims to investigate whether, in women with inverted nipples, the use of an inverted syringe increases the rate of exclusive breastfeeding at one month compared to standard care. One-hundred healthy women with grade 1 or 2 inverted nipples will be recruited as of 37 weeks of gestation. They will be randomly allocated to standard care (control group) or to an intervention group. The intervention consists of using an inverted syringe to evert the nipple before every breastfeed, starting with the first feed after delivery. The primary outcome measure is the rate of exclusive breastfeeding at 1 month. Secondary outcome measures include exclusive breastfeeding rates at 3 and 6 months, nipple eversion rate, successful latching rate, rates of any breastfeeding at 1, 3, and 6 months, breastfeeding-associated complications, maternal satisfaction with breastfeeding, maternal quality of life, and adverse events. Descriptive and regression analysis will be conducted under the intention to treat basis. DISCUSSION: The use of the inverted syringe to evert inverted nipples is a simple, inexpensive, and safe technique that can be performed by mothers with inverted nipples. Findings of this trial, if positive, will provide much needed evidence for a safe, affordable, readily available, and simple intervention to treat inverted nipples, and improve breastfeeding practice among affected women.

trial registrationClinicalTrials.gov, NCT03529630. Registered May 8, 2018.

Indexed as

LactationSyringesBreast DiseasesBreast FeedingFemaleHumansInfantInfant, NewbornLebanonNipplesRandomized Controlled Trials as TopicTime FactorsTreatment OutcomeBreastfeedingInverted nippleInverted syringe technique

Identifiers

PMID31842992
PMCPMC6916061
OpenAlexW2995328935

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.