Evidence map›Paper›PMID 31842979›Full record

ArticleSubstance abuse treatment, prevention, and policy2019

Evaluation of methanol content of illegal beverages using GC and an easier modified Chromotropic acid method; a cross sectional study.

Nasim Zamani, Ali Rafizadeh, Hossein Hassanian-Moghaddam, Alireza Akhavan-Tavakoli, Mahdi Ghorbani-Samin, Maryam Akhgari, Shahab Shariati

Open access · goldAbstract read
In one paragraph

Article in Substance abuse treatment, prevention, and policy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Methanol intoxication in the central region of Saudi Arabia: Five case studies.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Nasim ZamaniSocial Determinants of Health Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Ali RafizadehDepartments of Nursing & Midwifery, Rasht Branch, Islamic Azad University, Rasht, Iran.
Hossein Hassanian-MoghaddamSocial Determinants of Health Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran. hassanian@sbmu.ac.ir.ORCID 0000-0003-4370-0544
Alireza Akhavan-TavakoliLegal Medicine Research Center, Legal Medicine Organization, Rasht, Iran.
Mahdi Ghorbani-SaminLegal Medicine Research Center, Legal Medicine Organization, Rasht, Iran.
Maryam AkhgariDepartment of Forensic Toxicology, Legal Medicine Research Center, Legal Medicine Organization, Tehran, Iran.
Shahab ShariatiDepartment of Chemistry, Rasht Branch, Islamic Azad University, Rasht, Iran.
Iranian Legal Medicine Organization · IRIslamic Azad University Rasht Branch · IRShahid Beheshti University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMethanol is highly toxic to human beings and naturally exists in some beverages. Having access to an easy and cheap method for its determination is of great importance to increase the safety of use of these beverages. Our main aim is to evaluate methanol concentration of some alcoholic beverages in Iran black market and compare it with the European and US standards. Also, we evaluated the efficacy of a newly designed and produced chemical kit in determining the risk of methanol toxicity by drinking of such samples compared to gas chromatography method.

methodsMethanol content of suspected alcoholic beverages referred to forensic toxicology laboratory, Guilan province, Iran was measured using gas chromatography and a recently designed kit based on modified colorimetric chromotropic acid method.

resultsOf 1221 samples, 145 (11.9%) had no ethanol content, while in three samples (0.25%), methanol was high enough (700,000; 870,000; 920,000 mg/L) to cause severe methanol toxicity. Median [IQR] ethanol content of the suspected samples was 9% [3.7, 32.75]. Methanol was detected in 128 (10.48%) samples using gas chromatography method and 160 samples (13.1%) with designed kit with 100% sensitivity, 97.07% specificity, and 100% negative-predictive-value.

conclusionsAlcoholic beverages produced in local black market in Iran are not safe at all. The application of the new method is practical, rapid, easy, and accurate to evaluate the risk of methanol toxicity in suspected alcoholic drinks.

Indexed as

Alcoholic BeveragesChromatography, GasColorimetryCross-Sectional StudiesIranMethanolNaphthalenesulfonateschromotropic acidMethanolNaphthalenesulfonatesAlcoholic beveragesMethanolModified chromotropic acid method

Identifiers

PMID31842979
PMCPMC6916049
OpenAlexW2995411830

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.