Evidence map›Paper›PMID 31842816›Full record

ArticleBMC cancer2019

Mycotoxin exposure is associated with increased risk of esophageal squamous cell carcinoma in Huaian area, China.

Kathy S Xue, Lili Tang, Guiju Sun, Shaokang Wang, Xu Hu, Jia-Sheng Wang

Open access · goldAbstract read
In one paragraph

Article in BMC cancer, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
4.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 39 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Kathy S XueDepartment of Environmental Health Science, College of Public Health, University of Georgia, 150 Green Street, Athens, GA, 30602, USA.
Lili TangDepartment of Environmental Health Science, College of Public Health, University of Georgia, 150 Green Street, Athens, GA, 30602, USA.
Guiju SunSoutheast University School of Public Health, Nanjing, Jiangsu, China.
Shaokang WangSoutheast University School of Public Health, Nanjing, Jiangsu, China.
Xu HuHuaian District Center for Disease Control and Prevention, Huaian, Jiangsu, China.
Jia-Sheng WangDepartment of Environmental Health Science, College of Public Health, University of Georgia, 150 Green Street, Athens, GA, 30602, USA. jswang@uga.edu.ORCID http://orcid.org/0000-0002-8458-9187
University of Georgia · USSoutheast University · CNXian Center for Disease Control and Prevention · CN

Funding

Chemoprevention of Green Tea Polyphenol on Liver CancerR01CA090997 · NCI · UNIVERSITY OF GEORGIA · PI WANG, JIA-SHENG · 2003 to 2007
$1.8M
Validation of Fumonisin and Microcystin BiomarkersR21CA094683 · NCI · TEXAS TECH UNIVERSITY · PI WANG, JIA-SHENG · 2001 to 2003
$548k
NCI NIH HHS CA90997NCI NIH HHS CA94683NCI NIH HHS R01 CA090997NCI NIH HHS R21 CA094683
6 · The paper itself

Abstract

backgroundConsumption of moldy food has previously been identified as a risk factor for esophageal squamous cell carcinoma (ESCC) in high-risk countries; however, what contributing roles these dietary carcinogenic mycotoxins play in the etiology of ESCC are largely unknown.

methodsA mycotoxin biomarker-incorporated, population-based case-control study was performed in Huaian area, Jiangsu Province, one of the two high-risk areas in China. Exposure biomarkers of aflatoxins (AF) and fumonisins (FN) were quantitatively analyzed using HPLC-fluorescence techniques.

resultsAmong the cases (n = 190), the median levels of AF biomarker, serum AFB

conclusionsMycotoxin exposure, especially to AFB

Indexed as

Dietary ExposureAflatoxinsAgedBiomarkersChinaChromatography, High Pressure LiquidEsophageal NeoplasmsEsophageal Squamous Cell CarcinomaFemaleFood ContaminationFumonisinsHumansMaleMiddle AgedRisk FactorsAflatoxinsBiomarkersFumonisinsAflatoxin B1Co-exposureEsophageal cancerFumonisin B1Molecular epidemiologyMycotoxins

Identifiers

PMID31842816
PMCPMC6916103
OpenAlexW2996380275

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.